133095-96-2Relevant academic research and scientific papers
Conversion of a silylated hemiacetal into an α-bromoether using trimethylsilylbromide. Synthesis of platelet activating factor antagonist L-659,989
Thompson,Tschaen,Simpson,McSwine,Russ,Little,Verhoeven,Shinkai
, p. 6953 - 6956 (1990)
An efficient synthesis of platelet activating factor antagonist L-659,989 has been achieved in ten steps from commercially available 5-iodovanillin. The key transformation converts a silylated hemi-acetal into an α-bromoether followed by a highly stereose
