133382-98-6

Upstream product

• 30189-48-1 (S)-tert-butyl (1-hydrazinyl-1-oxo-3-phenylpropan-2-yl)carbamate 
• 79-06-1 2-propenamide 

Downstream Products

• 222853-56-7 N'-(2-tert-butoxycarbonylamino-3-phenyl-propionyl)-N-(2-carbamoyl-ethyl)-hydrazinecarboxylic acid benzyl ester 
• 222853-58-9 N'-(2-tert-butoxycarbonylamino-3-phenyl-propionyl)-N-(2-carbamoyl-ethyl)-hydrazinecarboxylic acid 2,2,2-trichloro-ethyl ester 
• 133383-06-9 (N-tert-butoxycarbonyl-L-phenylalanyl)(2-azaglutaminyl)glycine 
• 222853-54-5 N'-(2-tert-butoxycarbonylamino-3-phenyl-propionyl)-N-(2-carbamoyl-ethyl)-hydrazinecarboxylic acid phenyl ester 
• 133383-03-6 ethyl (N-tert-butoxycarbonyl-L-phenylalanyl)(2-azaglutaminyl)glycinate 

Relevant academic research and scientific papers

Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease

A series of azapeptides was prepared and assessed as inhibitors of the human rhinovirus 3C protease. Boc-VLFaQ-OPh was a slow-turnover substrate that gave transient (ca. 1-2 h) inhibition as it underwent hydrolysis. Boc- VLFaG-OPh gave very slow but essen

Synthesis and spectroscopic properties of azaglutamine amino acid and peptide derivatives

tert-Butyl carbazate and Boc-amino acid hydrazides undergo a Michael addition with acrylamide to give substituted carbazates having the side-chain of glutamine on nitrogen. These carbazates may react with chloroformates to give protected azaglutamine esters, and N-activated amino acid esters to give azaglutamine peptides.