222853-58-9Relevant academic research and scientific papers
Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease
Venkatraman, Shankar,Kong, Jian-she,Nimkar, Sanjay,Wang, Q. May,Aube, Jeffrey,Hanzlik, Robert P.
, p. 577 - 580 (2007/10/03)
A series of azapeptides was prepared and assessed as inhibitors of the human rhinovirus 3C protease. Boc-VLFaQ-OPh was a slow-turnover substrate that gave transient (ca. 1-2 h) inhibition as it underwent hydrolysis. Boc- VLFaG-OPh gave very slow but essen
