1333981-84-2

Usage

Uses

Used in Chemical Synthesis:
N-[(1R,2R)-1,2-Diphenyl-2-(2-(4-Methylbenzyloxy)ethylaMino)-ethyl]-4-Methylbenzene sulfonaMide(chloro)rutheniuM(II) (R,R)-Ts-DENEB 1333981-84-2 is used as a catalyst for asymmetric hydrogen transfer reactions. It is instrumental in the synthesis of 2-(1,2,3,4-tetrahydro-1-isoquinolyl)ethanol derivatives, which are important intermediates in the production of pharmaceuticals and other specialty chemicals.
Used in Hydrogen Carrier Systems:
In the field of renewable energy and green chemistry, (R,R)-Ts-DENEB is used to form hydrogen carrier systems. It facilitates the catalytic dehydrogenative coupling of methanol and 1,2-diamine, enabling the generation of hydrogen (H2) without the production of carbon dioxide (CO2). This process is significant for developing sustainable methods to produce hydrogen, a clean energy carrier, and reducing the environmental impact of hydrogen production.
Used in Pharmaceutical Industry:
N-[(1R,2R)-1,2-Diphenyl-2-(2-(4-Methylbenzyloxy)ethylaMino)-ethyl]-4-Methylbenzene sulfonaMide(chloro)rutheniuM(II) (R,R)-Ts-DENEB 1333981-84-2 is used as a catalyst in the pharmaceutical industry for the production of enantiomerically pure compounds. The ability to selectively produce one enantiomer over another is crucial in drug synthesis, as different enantiomers can have vastly different biological activities and pharmacological effects.
Used in Environmentally Friendly Processes:
N-[(1R,2R)-1,2-Diphenyl-2-(2-(4-Methylbenzyloxy)ethylaMino)-ethyl]-4-Methylbenzene sulfonaMide(chloro)rutheniuM(II) (R,R)-Ts-DENEB 1333981-84-2 is also used in processes aimed at reducing the environmental footprint of chemical production. By enabling the generation of hydrogen without CO2 emissions, (R,R)-Ts-DENEB contributes to the development of more sustainable and eco-friendly chemical processes, which is particularly important in industries striving to minimize their carbon footprint and environmental impact.

Reaction

Catalyst used for asymmetric -transfer hydrogenation. Catalyst used for asymmetric H2 – hydrogenation. 3. Catalyst used for dynamic kinetic resolution.

Upstream product

• 3973-18-0 2-(prop-2-ynyloxy)ethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 144222-34-4 (R,R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine 
• 78-79-5 isoprene 
• 1242103-61-2 N-((1R,2R)-2-(2-hydroxyethylamino)-1,2-diphenylethyl)-4-methylbenzenesulfonamide 
• 1333982-07-2 [RuCl₂(1-(bromomethyl)-4-methylbenzene)]2 

Downstream Products

• 1333981-88-6 RuCl((R,R)-O-HT-Tsdpen) 
• 1360897-49-9 Ru((R,R)-O-HT-Tsdpen) 

Relevant academic research and scientific papers

RUTHENIUM-DIAMINE COMPLEXES AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS

Provided is a catalyst for asymmetric reduction, which can be produced by a convenient and safe production method, has a strong catalytic activity, and has excellent stereoselectivity. The present invention relates to a ruthenium complex represented by the following formula (1): wherein R1 represents an alkyl group or the like; Y represents a hydrogen atom; X represents a halogen atom or the like; j and k each represent 0 or 1; R2 and R3 each represent an alkyl group or the like; R11 to R19 each represent a hydrogen atom, an alkyl group or the like; Z represents oxygen or sulfur; n1 represents 1 or 2; and n2 represents an integer from 1 to 3, a method for producing the ruthenium complex, a catalyst for asymmetric reduction formed from the ruthenium complex, and methods for selectively producing an optically active alcohol and an optically active amine using the catalyst for asymmetric reduction.