1334177-84-2 Usage
Uses
Used in Pharmaceutical Industry:
PEG9-t-butyl ester is used as a pharmaceutical excipient for improving the solubility and bioavailability of drugs. The hydrophilic PEG spacer increases the solubility of hydrophobic drugs in aqueous media, while the hydroxyl group allows for the attachment of drugs or other functional groups.
Used in Drug Delivery Systems:
PEG9-t-butyl ester is used as a component in drug delivery systems, such as nanoparticles, liposomes, and hydrogels, to enhance the stability, targeting, and controlled release of therapeutic agents. The hydrophilic PEG spacer provides steric stabilization and reduces the immunogenicity and non-specific interactions with biological systems.
Used in Bioconjugation:
PEG9-t-butyl ester is used as a bioconjugation agent to attach biologically active molecules, such as peptides, proteins, and nucleic acids, to various surfaces or carriers. The hydroxyl group allows for the covalent attachment of these molecules, while the PEG spacer provides a hydrophilic and flexible linker.
Used in Cosmetics and Personal Care Industry:
PEG9-t-butyl ester is used as an ingredient in cosmetics and personal care products, such as creams, lotions, and shampoos, to improve the solubility, stability, and sensory properties of the formulations. The hydrophilic PEG spacer and the hydroxyl group contribute to the emulsification, dispersion, and moisturizing effects of the products.
Used in Chemical Synthesis:
PEG9-t-butyl ester is used as a protected intermediate in the synthesis of various PEGylated compounds, such as PEGylated drugs, polymers, and surfactants. The t-butyl protected carboxyl group can be selectively deprotected under acidic conditions, allowing for further reactions and functionalization.
Check Digit Verification of cas no
The CAS Registry Mumber 1334177-84-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,4,1,7 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1334177-84:
(9*1)+(8*3)+(7*3)+(6*4)+(5*1)+(4*7)+(3*7)+(2*8)+(1*4)=152
152 % 10 = 2
So 1334177-84-2 is a valid CAS Registry Number.
1334177-84-2Relevant academic research and scientific papers
DIRECTED CONJUGATION TECHNOLOGIES
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Paragraph 0575; 0576, (2021/05/29)
Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, provided technologies are useful for preparing antibody conjugates.
A-amido glycol propionic acid preparation method (by machine translation)
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Paragraph 0022, (2017/10/22)
The invention discloses a-amido glycol propionic acid (NH2 - PEGn - CH2 CH2 C00H, n=1 - 24) of the preparation method, the preparation method in order to mono-disperse small molecular double-hydroxy polyethylene
