Welcome to LookChem.com Sign In|Join Free
  • or
H2N-PEG8-tBu, also known as Amino-PEG8-t-butyl ester, is a monodisperse PEG linker that contains an amino group with a t-butyl protected carboxyl group. This unique structure allows the amino group to be reactive with various functional groups such as carboxylic acids, activated NHS esters, and carbonyls (ketone, aldehyde), while the t-butyl protected carboxyl group can be deprotected under acidic conditions. H2N-PEG8-tBu is primarily used in the synthesis of antibody drug conjugates (ADCs) as a cleavable 8-unit PEG-ADC linker.

756526-06-4

Post Buying Request

756526-06-4 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

756526-06-4 Usage

Uses

Used in Pharmaceutical Industry:
H2N-PEG8-tBu is used as a cleavable 8-unit PEG-ADC linker for the synthesis of antibody drug conjugates (ADCs). The application reason is that it provides a stable and biocompatible linker for the covalent attachment of cytotoxic drugs to antibodies, enhancing the targeted delivery of these drugs to cancer cells and reducing side effects on healthy cells.
Additionally, H2N-PEG8-tBu can be used in other industries where stable and biocompatible linkers are required for the conjugation of biological molecules, such as in the development of targeted drug delivery systems, biosensors, and diagnostic tools.

Check Digit Verification of cas no

The CAS Registry Mumber 756526-06-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,6,5,2 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 756526-06:
(8*7)+(7*5)+(6*6)+(5*5)+(4*2)+(3*6)+(2*0)+(1*6)=184
184 % 10 = 4
So 756526-06-4 is a valid CAS Registry Number.

756526-06-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name amino-dPEG8.(TM).-t-butyl ester

1.2 Other means of identification

Product number -
Other names H2N-PEG8-CH2CH2COOtBu

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:756526-06-4 SDS

756526-06-4Relevant academic research and scientific papers

A-amido glycol propionic acid preparation method (by machine translation)

-

, (2017/10/22)

The invention discloses a-amido glycol propionic acid (NH2 - PEGn - CH2 CH2 C00H, n=1 - 24) of the preparation method, the preparation method in order to mono-disperse small molecular double-hydroxy polyethylene

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 756526-06-4