133433-34-8

Basic information

• Product Name: 5-chloro-2-<(carboxymethyl)amino>-benzoic acid
• Synonyms: 5-chloro-2-<(carboxymethyl)amino>-benzoic acid
• CAS NO: 133433-34-8
• Molecular Weight: 229.62
• Mol File: 133433-34-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-<(carboxymethyl)amino>-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-<(carboxymethyl)amino>-benzoic acid(133433-34-8)
• EPA Substance Registry System: 5-chloro-2-<(carboxymethyl)amino>-benzoic acid(133433-34-8)

Safety Data

• Hazardous Substances Data: 133433-34-8(Hazardous Substances Data)

Upstream product

• 612-42-0 phenylglycine-o-carboxylic acid 
• 79-11-8 chloroacetic acid 
• 635-21-2 5-chloroanthranilic acid 
• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 1223386-17-1 C₁₁H₁₂ClNO₄ 
• 21739-93-5 2-bromo-5-chlorobenzoic acid 
• 56-40-6 glycine 
• 50-79-3 2,5-dichlorobenzoic acid 
• 7782-50-5 chlorine 
• 64-19-7 acetic acid 

Downstream Products

• 21716-60-9 5-Chlor-2-methoxycarbonylmethylamino-benzoesaeuremethylester 
• 700838-62-6 [2-(1-(2'-bromobenzenesulfonyl)-5-chloro-1H-indol-3-yloxy)ethyl]dimethylamine 
• 1310369-78-8 C₁₉H₂₀BrClN₂O₃S 
• 1310369-79-9 C₁₉H₂₀BrClN₂O₃S 
• 62486-02-6 1-acetyl-5-chloro-1,2-dihydro-3H-indol-3-one 
• 108761-32-6 1-acetyl-5-chloro-1H-indol-3-yl acetate 

Relevant articles and documents

Total Synthesis of the Chlorinated Indigo-N-Glycosides Akashin A, B and C

A total synthesis of the indigo-derived natural products akashin A-C was developed. The key step was the N-glycosylation of soluble N-benzylated-indigos with a suitably protected viosaminyl trichloroacetimidate. This donor was obtained from D-galactose. U

Indoxyl-based umpolung strategy for the synthesis of unsymmetrical 3,3′-biindoles

3,3′-Bisindoles are known to be important structural motifs found in bioactive natural products, pharmaceuticals, and functional materials. Herein, a novel indoxyl-based approach was established for the synthesis of unsymmetrical 3,3′-biindoles from indoles and indoxyls. This approach generated moderate to excellent yields of the desired products (24 examples, up to 98% yield). The present method features broad substrate scope, operational simplicity, high atom economy, and utilization of non-toxic and inexpensive molecular iodine as catalyst. The applicability of this method has been demonstrated by the facile gram-scale synthesis.

INDIRUBIN-3'-OXIME DERIVATIVES AS POTENT CYCLIN DEPENDENT KINASE INHIBITORS

The present invention relates to an indirubin-3'-oxime derivative as potent cyclin dependent kinase inhibitor with anti-cancer activity. More particularly, this invention relates to an indirubin-3'-oxime derivative as potent cyclin dependent kinase inhibitor having excellent anti-cancer activity against human lung cancer cell, human fibro sarcoma cell, human colon cancer cell, human leukemia cell, human stomach cancer cell, human nasopharyngeal cancer cell and/or human breast cancer cell.