1334493-41-2Relevant academic research and scientific papers
Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein
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Page/Page column 226-228; 253; 258-259, (2019/02/14)
In one aspect, the invention relates to substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs, derivatives thereof, and related compounds, which are useful as inhibitors of STAT protein activity; synthetic methods for making the com
Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain
Page, Brent D.G.,Fletcher, Steven,Yue, Peibin,Li, Zhihua,Zhang, Xiaolei,Sharmeen, Sumaiya,Datti, Alessandro,Wrana, Jeffrey L.,Trudel, Suzanne,Schimmer, Aaron D.,Turkson, James,Gunning, Patrick T.
, p. 5605 - 5609 (2011/10/09)
Signal transducer and activator of transcription 3 (Stat3) protein is a cytosolic transcription factor that is aberrantly activated in numerous human cancers. Inhibitors of activated Stat3-Stat3 protein complexes have been shown to hold therapeutic promis
