1334748-49-0

Basic information

• Product Name: trans-3-[2-[2-(4-bromophenyl)ethenyl]phenyl]sydnone
• CAS NO: 1334748-49-0
• Molecular Weight: 343.18
• Mol File: 1334748-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-3-[2-[2-(4-bromophenyl)ethenyl]phenyl]sydnone(CAS DataBase Reference)
• NIST Chemistry Reference: trans-3-[2-[2-(4-bromophenyl)ethenyl]phenyl]sydnone(1334748-49-0)
• EPA Substance Registry System: trans-3-[2-[2-(4-bromophenyl)ethenyl]phenyl]sydnone(1334748-49-0)

Safety Data

• Hazardous Substances Data: 1334748-49-0(Hazardous Substances Data)

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 106412-78-6 3-(2-hydroxymethylphenyl)sydnone 
• 64241-58-3 3-(o-Carboxyphenyl)sydnone methyl ester 
• 64241-57-2 N-[2-(methyloxycarbonyl)phenyl]glycine 
• 64241-56-1 2-(carboxymethyl-nitroso-amino)-benzoic acid methyl ester 
• 106-38-7 para-bromotoluene 

Relevant articles and documents

Synthesis of 3-(o-stilbenyl)sydnone and 3-(o-stilbenyl)-4- substitutedsydnone derivatives and their antitumor evaluation

A series of novel stilbene-sydnone derivatives were synthesized by the following sequence of reactions: Starting from methyl anthranilate via glycine- and nitrosoglycine derivatives the corresponding 3-(o-carbomethoxyphenyl)-4-H/ Me/Ph-sydnones were prepared and transformed to 3-(o-formylphenyl)-4-H/Me/Ph- sydnones, starting materials for Wittig reaction with various phosphonium salts to stilbenylsydnone derivatives. Final products were evaluated for their cytotoxic properties on five cancer cell lines, whereby the cis-4-methyl-3-[2- [2-(4-methylphenyl)ethenyl]phenyl]sydnone 5 and cis-4-phenyl-3-[2-[2-(4- chlorophenyl)ethenyl]-phenyl]sydnone 10 showed the most pronounced activity. ARKAT-USA, Inc.