64241-57-2Relevant academic research and scientific papers
Heumann indole flow chemistry process
Crifar, Cynthia,Dücker, Fenja L.,Nguyen Thanh, Sacha,Kairouz, Vanessa,Lubell, William D.
, p. 10929 - 10937 (2019/08/26)
Continuous flow chemistry has improved efficiency in the Heumann indole process. 3-Substituted indoles were prepared by three flow steps performed in succession in better overall yield and shorter reaction times relative to their batch counterparts. Novel
Synthesis of 3-(o-stilbenyl)sydnone and 3-(o-stilbenyl)-4- substitutedsydnone derivatives and their antitumor evaluation
Butkovic, Kristina,Marinic, Zeljko,Sindler-Kulyka, Marija
experimental part, p. 1 - 15 (2011/09/16)
A series of novel stilbene-sydnone derivatives were synthesized by the following sequence of reactions: Starting from methyl anthranilate via glycine- and nitrosoglycine derivatives the corresponding 3-(o-carbomethoxyphenyl)-4-H/ Me/Ph-sydnones were prepared and transformed to 3-(o-formylphenyl)-4-H/Me/Ph- sydnones, starting materials for Wittig reaction with various phosphonium salts to stilbenylsydnone derivatives. Final products were evaluated for their cytotoxic properties on five cancer cell lines, whereby the cis-4-methyl-3-[2- [2-(4-methylphenyl)ethenyl]phenyl]sydnone 5 and cis-4-phenyl-3-[2-[2-(4- chlorophenyl)ethenyl]-phenyl]sydnone 10 showed the most pronounced activity. ARKAT-USA, Inc.
Preparation and Properties of Organic Polymer Ferromagnet with Indigo Unit
Tanaka, Hitoshi,Tokuyama, Kouichi,Sato, Tsuneyuki,Ota, Tadatoshi
, p. 1813 - 1816 (2007/10/02)
A new organic polymer ferromagnet with indigo unit in the main chain was prepared and its magnetic properties were examined.Resulting polymer contained the fraction which attracted to a permanent magnet and it showed a definitive hysteresis loop at room t
