133840-72-9

Basic information

• Product Name: 3H-1,2,4-Triazol-3-one, 2-(4-chlorophenyl)-1,2-dihydro-5-methyl-
• CAS NO: 133840-72-9
• Molecular Formula: C9H8ClN3O
• Molecular Weight: 209.635
• Mol File: 133840-72-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3H-1,2,4-Triazol-3-one, 2-(4-chlorophenyl)-1,2-dihydro-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-1,2,4-Triazol-3-one, 2-(4-chlorophenyl)-1,2-dihydro-5-methyl-(133840-72-9)
• EPA Substance Registry System: 3H-1,2,4-Triazol-3-one, 2-(4-chlorophenyl)-1,2-dihydro-5-methyl-(133840-72-9)

Safety Data

• Hazardous Substances Data: 133840-72-9(Hazardous Substances Data)

Upstream product

• 108-90-7 chlorobenzene 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 106-47-8 4-chloro-aniline 
• 24660-31-9 acetaldehyde 4-chlorophenylhydrazone 
• 22863-24-7 5-methyl-2-phenyl-2,4-dihydro-[1,2,4]triazol-3-one 
• 133902-74-6 4-acetyl-1-(4-chlorophenyl)-3,3-dimethyl-1,2,4-triazolidin-5-one 
• 269392-85-0 3-(4-chlorophenyl)-5-methyl-2-oxo-Δ⁴-1,3,4-oxadiazole 
• 1200-11-9 Acetone (4-Chlorophenyl)hydrazone 

Downstream Products

• 111992-16-6 4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichlorophenyl)-1,2,4-triazol-5(1H)-one 
• 155431-73-5 2-(4-chlorophenyl)-4-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3(2H,4H)-1,2,4-triazolone 

Relevant articles and documents

Synthesis method of metolachlor intermediate

The synthesis method comprises the following steps: S1) nitration reaction of chlorobenzene in a nitration reagent to obtain a mixture of o-chloronitrobenzene and p-chloronitrobenzene without separation. S2) The mixture of o-chloronitrobenzene and p-chloronitrobenzene is subjected to catalytic hydrogenation reaction to obtain the mixture of o-chloroaniline and p-chloroaniline, and the product does not need to be separated. S3) The mixture of o-chloroaniline and chloroaniline is subjected to diazotization reaction to obtain the mixture of o-chlorophenylhydrazine and p-chlorophenylhydrazine, and the product does not need to be separated. S4) The mixture of o-chlorophenylhydrazine and p-chlorophenylhydrazine and aldehyde are subjected to a condensation reaction to obtain a triazole ring mixture of Formulae I through a and I through b. S5) The triazole ring mixture is subjected to chlorination reaction to obtain the metolachlor intermediate shown in the formula I. 2, 4 - Dichloroaniline is used as a raw material, the production cost of the metolachlor is reduced, and the supply limitation of the raw material is avoided.

C5-Alkyl-1,3,4-Oxadiazol-2-ones Undergo Dealkylation upon Nitrogen Insertion to Form 2H-1,2,4-Triazol-3-ones: Synthesis of 1,2,4-Triazol-3-one Hybrids with Triazolothiadiazoles and Triazolothiadiazines

The present study emphasizes on the dealklylation of 3-aryl-5-alkyl-2-oxo-Δ4-1,3,4-oxadiazoles when reacted with formamide resulting in the formation of 2-aryl-2H-1,2,4-triazol-3(4H)-ones as major product. Subsequent reactions of 2-aryl-2H-1,2,

Azole compounds, their production and use

An azole compound represented by the formula (I): STR1 wherein Ar is a substituted phenyl group; R1 and R2 independently are a hydrogen atom or a lower alkyl group, or R1 and R2 may combine together to form a lower alkylene group; R3 is a group bonded through a carbon atom; R4 is a hydrogen atom or an acyl group; X is a nitrogen atom or a methine group; and n Y and Z independently are a nitrogen atom or a methine group which may optionally be substituted with a lower alkyl group, or a salt thereof, which is useful for prevention and therapy of fungal infections of mammals as antifungal agent.