1338594-75-4

Upstream product

• 1338594-66-3 C₁₆H₁₄O₃ 
• 1338594-60-7 C₃₃H₅₁N₃O₆Si 
• 90-76-6 2-deoxy-2-amino glucose 
• 164014-40-8 2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one 
• 378242-08-1 2,2-dimethyl-5-vinyl-4H-benzo[d][1,3]dioxin-4-one 
• 154714-19-9 5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 303-07-1 2,6-Dihydroxybenzoic acid 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 1338594-62-9 phenyl 2-azido-2-deoxy-4-O-p-methoxybenzyl-1-thio-3-O-triisopropylsilyl-D-glucopyranose 
• 1338594-65-2 (2S,3R,4R,5R)-6-(allyloxy)-2-azido-5-(benzyloxy)-4-O-p-methoxybenzyl-3-O-triisopropylsilyl-hexyl 2-hydroxy-6-vinylbenzoate 
• 100-39-0 benzyl bromide 
• 1338594-64-1 2-azido-5-O-benzyl-2-deoxy-4-O-p-methoxybenzyl-1-O-pivaloyl-3-O-triisopropylsilyl-D-sorbitol 
• 1338594-63-0 2-azido-2-deoxy-4-O-p-methoxybenzyl-3-O-triisopropylsilyl-D-sorbitol 

Downstream Products

• 1338594-58-3 C₃₇H₄₅N₃O₈ 

Relevant academic research and scientific papers

SOMATOSTATIN MIMETICS

Somatostatin is a tetradecapeptide that regulates, through binding to its receptors (SSTRs), a number of processes including the release of growth hormone and other pituitary hormones. Disclosed herein are a number of somatostatin mimetics that exhibit potential utility as therapeutic agents. Formula (I)

Synthesis of a benzomacrolactone-based somatostatin mimetic

The benzomacrolactone is a framework found in numerous natural products. The synthesis of an orthogonally functionalized benzomacrolactone from d-glucosamine and a salicylic acid derivative is described. This macrolactone was used for the synthesis of a somatostatin mimetic that has submicromolar affinity for the human somatostatin receptor 4 (hSSTR4).