133963-99-2Relevant academic research and scientific papers
Asymmetric Aldol Reaction between Achiral Silyl Enol Ethers and Achiral Aldehydes by Use of a Chiral Promoter System
Kobayashi, Shu,Uchiro, Hiromi,Fujishita, Yuko,Shiina, Isamu,Mukaiyama, Teruaki
, p. 4247 - 4252 (1991)
In the presence of a chiral promoter consisting of tin(II) triflate, a chiral diamine, and tributyltin fluoride, the silyl enol ether of S-ethyl ethanethioate or S-tert-butyl ethanethioate reacts with aldehydes to afford the corresponding aldol-type adduc
The catalytic asymmetric aldol reaction of aldehydes with unsubstituted and monosubstituted silyl ketene acetals: Formation of anti-β-hydroxy-α-methyl esters
Parmee,Hong,Tempkin,Masamune
, p. 1729 - 1732 (2007/10/02)
The title rection with unsubstituted and monosubstituted silyl ketene acetals proceeds with high enantioselectivity, and in the latter case good diastereoselectivity favoring the anti-β-hydroxy-α-methyl esters in all reported cases.
Perfect Stereochemical Control in the Synthesis of syn-α-Methyl-β-hydroxy Thioesters by Asymmetric Aldol Reaction of Silyl Enol Ethers with Aldehydes
Mukaiyama, Teruaki,Uchiro, Hiromi,Kobayashi, Shu
, p. 1001 - 1004 (2007/10/02)
Perfect stereochemical control in the synthesis of syn-α-methyl-β-hydroxy thioesters are achieved by the asymmetric aldol reaction between silyl enol ether of S-ethyl propanethioate and aldehydes by the use of a chiral promoter consisted of chiral diamine
