13404-00-7

Upstream product

• 124-40-3 dimethyl amine 
• 886-38-4 diphenylcyclopropenone 
• 58085-33-9 α-phenylcinnamoyl chloride 
• 1483-82-5 phenylethynyl chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 501-65-5 diphenyl acetylene 
• 932-87-6 1-Bromo-2-phenylacetylene 

Downstream Products

• 25341-20-2 cis-α-Phenylcinnamic acid dimethylamide 
• 961-42-2 N,N-dimethyl 2,3-diphenyl propanamide 
• 25341-38-2 (E)-N,N-dimethyl-2,3-diphenyl-2-propen-1-ylamine 
• 25341-39-3 (2,3-diphenyl-allyl)-dimethyl-amine 

Relevant academic research and scientific papers

Palladium-catalyzed intermolecular addition of formamides to alkynes

A novel palladium system for an intermolecular addition of formamides to alkynes has been developed. The reaction of formamides with internal alkynes in the presence of a palladium catalyst with acid chloride as an additive afforded (E)-α,β-unsaturated amides regio- and stereoselectively. The same catalyst system realized the first example of the addition of formamides to terminal alkynes giving the corresponding α,β-unsaturated amides bearing a terminal methylene moiety as major products. The present reaction was widely applicable to substrates with various functionalities. This method also could be applied to the reaction of N,N-disubstituted formamides with norbornene. A hydridopalladium species would be formed as a key intermediate with in situ generated HCl under the reaction conditions.

Substituent Effects on the CC Bond Strength, 17. - Formation and Stability of α-Carbamoylbenzyl Radicals

Products and kinetics of the homolytic thermolyses reactions of the three tertiary amides 6a-c of 2,3,3-triphenylpropanoic acid were studied in solution.The steric effects on the C-C bond homolysis processes were evaluated from MM2 calculations.Taking this into account, we deduced radical stabilization enthalpies RSE for the α-carbamoylbenzyl radicals 3a-c from the activation enthalpies ΔH(excit.) . - Key Words: Bond cleavage, C-C kinetics of / Radicals, stability of

On the Reaction of Diphenylcyclopropenone, its Functional Derivatives and Imonium Salts with Amines

The reactions of cyclopropenones 1, 2, cyclopropenone imines 3 and cyclopropenone imonium cations 5 with amines of different type are investigated and the structure of the products obtained is elucidated by means of spectral data and chemical behavior.The possible reaction modes and mechanisms are discussed.