1340593-59-0

Usage

Uses

Used in Pharmaceutical Industry:
(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-ylpropan-2-ol is used as a pharmaceutical compound for its potential therapeutic effects. The presence of various functional groups in the molecule may allow it to interact with biological targets and exhibit pharmacological activity.
Used in Materials Science:
(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-ylpropan-2-ol is used in materials science for its potential applications in the development of new materials with unique properties. The combination of different functional groups in the molecule may enable the creation of materials with specific characteristics, such as improved stability, reactivity, or selectivity.

Upstream product

• 1340593-92-1 C₂₂H₁₄F₇NO₂ 
• 288-94-8 2H-tetrazole 
• 624-28-2 2,5-dibromopyridine 
• 294181-95-6 2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester 
• 294182-06-2 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone 
• 294182-28-8 5-bromo-2-((-2-(2,4-difluorophenyl)oxiran-2-yl)difluoromethyl)pyridine 
• 886528-42-3 4,4,5,5-tetramethyl-2-(4-(2,2,2-trifluoroethoxy)phenyl)-1,3,2-dioxaborolane 
• 106-41-2 4-bromo-phenol 
• 106854-77-7 1-bromo-4-(2,2,2-trifluoro-ethoxy)benzene 
• 1340593-59-0 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol 
• 122-51-0 orthoformic acid triethyl ester 
• 149-73-5 trimethyl orthoformate 
• 348-57-2 2,4-difluorobromobenzene 

Downstream Products

• 1340593-60-3 C₃₀H₂₇F₇N₆O₅ 
• 1340593-84-1 C₃₁H₂₉F₇N₆O₅ 
• 1340593-85-2 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-yl 2-aminoacetate hydrochloride 
• 1340593-83-0 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-yl 3-aminopropanoate hydrochloride 
• 1446515-63-4 C₃₇H₂₉F₇N₅O₅P 
• 1446515-59-8 2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-yl dihydrogen phosphate 

Relevant academic research and scientific papers

Fungal lanosterol 14α-demethylase (CYP51) inhibitor Treatment of recurrent vulvovaginal candidiasis Treatment of onychomycosis

Developing a rationally designed, more selective azole antifungal agent that specifically targets the fungal CYP51 over the host CYP51 is a severe unmet need considering a massive shortfall in novel antifungal agents. In this context, oteseconazole (VT-1161) represents a very exciting new development targeting serious fungal infections caused by a wide variety of fungal pathogens including multidrug-resistant Candida responsible for recurrent vulvovaginal candidiasis. This monograph details the various in vitro and in vivo properties exhibited by oteseconazole as well as its current status in clinical trials.

METALLOENZYME INHIBITOR COMPOUNDS

The present disclosure describes compounds having agricultural fungicidal activity.

METALLOENZYME INHIBITOR COMPOUNDS

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

METALLOENZYME INHIBITOR COMPOUNDS

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.