134197-95-8

Upstream product

• 84184-51-0 (E)-methyl 3-(4-(benzyloxy)phenyl)acrylate 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 100-39-0 benzyl bromide 
• 6272-45-3 (E)-4-benzyloxycinnamic acid 
• 7400-08-0 para-coumaric acid 

Downstream Products

• 915396-55-3 (S)-2-hydroxy-3-(4-hydroxyphenyl)-N-methoxy-N-methylpropanamide 
• 1236191-25-5 (S)-2-((tert-butyldimethylsilyl)oxy)-3-(4-((tert-butyldimethylsilyl)oxy)phenyl)-N-methoxy-N-methylpropanamide 
• 134198-03-1 1-[(1S,2S)-2-(4-Benzyloxy-phenyl)-cyclopropyl]-ethanone 
• 75676-91-4 1-(4-benzyloxyphenyl)but-1-en-3-one 
• 134198-04-2 (1S,2S)-2-(4-Benzyloxy-phenyl)-cyclopropanecarboxylic acid methoxy-methyl-amide 

Relevant academic research and scientific papers

Total Synthesis of (+)-Vicenin-2

The bis-C-glucosyl flavonoid vicenin-2 (1) has been synthesized by exploiting bis-C-glycosylation of 1,3,5-trifluorobenzene and aromatic nucleophilic substitution to transform fluorine atoms to oxygen functions in excellent yield.

Concise access toward chiral hydroxy phenylpropanoids: formal synthesis of virolongin B; kigelin; kurasoin A; 4-hydroxysattabacin, and actinopolymorphol A

A simple, two step strategy consisting of Sharpless asymmetric dihydroxylation followed by regioselective breaking of [Formula presented] bond is utilized to target key chiral intermediates of natural products virolongin B, kigelin, kurasoin A, 4-hydroxy-sattabacin, and actinopolymorphol A. Derivatives of enantiopure hydroxy phenyl propanoids and α-hydroxy Weinreb amides are synthesized. The reductive cleavage of [Formula presented] bond in a regioselective manner is obtained using Pd/C in methanol.