75676-91-4Relevant articles and documents
Synthesis and cell growth inhibitory properties of substituted (E)-1-phenylbut-1-en-3-ones
Ducki, Sylvie,Hadfield, John A.,Hepworth, Lucy A.,Lawrence, Nicholas J.,Ching-Ying, Liu,McGown, Alan T.
, p. 3091 - 3094 (2007/10/03)
A series of (E)-1-phenylbut-1-en-3-ones, based on the naturally occurring (E)-1-(4'-hydroxyphenyl)but-1-en-3-one [IC50 (K562) 60 μM], was synthesised and screened for cytotoxic activity against the K562 human leukaemia cell line. (E)-1-(Pentafluorophenyl)but-1-en-3-one [IC50 (K562) 1.8 μM] was found to be over 30-fold more active than 1.
A novel route to cyclopropyl ketones, aldehydes, and carboxylic acids
Rodriques, Karen E.
, p. 1275 - 1278 (2007/10/02)
Cyclopropanation of α,β-unsaturated N-methoxy-N-methyl amides provided the cyclopropyl amides in far superior yields to those obtained with the corresponding ketones. The desired ketones are then readily accessible by the addition of organometallic reagents. Access to a variety functional groups, including aldehydes and carboxylic acids, is also described.
Substituted cyclohexanediones and their herbicidal uses
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, (2008/06/13)
The present disclosure is directed to substituted cyclohexanedione compounds, the preparation of said compounds, compositions containing said compounds and the use of said compositions in the selective pre- and postemergent kill and control of grassy weed