134249-43-7Relevant academic research and scientific papers
Asymmetric reductions of (Trifluoroacetyl)biphenyl derivatives with bakers'yeast and with Geotrichum candidum acetone powder
Fujisawa, Tamotsu,Onogawa, Yoshio,Sato, Akira,Mitsuya, Takeshi,Shimizu, Makoto
, p. 4267 - 4276 (1998)
The bakers' yeast reduction of (trifluoroacetyl)biphenyl derivatives produces (R)trifluoromethyl biphenylyl carbinols in high enantioselectivity, whereas the reduction of the same derivatives with Geotrichum candidum acetone powder gives the corresponding (S)-carbinols in excellent yields and enantioselectivity.
Synthesis of optically active 4,4,4-trifluoro-3-{4-(4-methoxyphenyl)phenyl}butanoic acid and its application to chiral dopant for nematic liquid crystals
Tojo, Kenta,Aoki, Yoshio,Yasutake, Mikio,Hirose, Takuji
, p. 620 - 626 (2006)
We synthesized an optically active 4,4,4-trifluoro-3-{4-(4-methoxyphenyl)phenyl}butanoic acid (5*). New chiral dopants for nematic liquid crystals were derived from (R)-(-)-5*, and their helical twisting power (HTP) values were measured. Their HTP values were largely influenced by the linkage between the asymmetric frame and the core moiety. The chiral dopant, (R)-(+)-4,4,4-trifluoro-1-(4-hexyloxyphenyl)-3-{4-(4-methoxyphenyl)phenyl}-1-butanone ((R)-(+)-7*) showed the largest HTP value (-21.7 μm-1).
