13436-49-2

Basic information

• Product Name: 1H-Indazole, 1-acetyl- (7CI,8CI,9CI)
• Synonyms: 1H-Indazole, 1-acetyl- (7CI,8CI,9CI)
• CAS NO: 13436-49-2
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17262
• Product Categories: ACETYLGROUP
• Mol File: 13436-49-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 306.8°Cat760mmHg
• Flash Point: 139.3°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 0.000756mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Indazole, 1-acetyl- (7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indazole, 1-acetyl- (7CI,8CI,9CI)(13436-49-2)
• EPA Substance Registry System: 1H-Indazole, 1-acetyl- (7CI,8CI,9CI)(13436-49-2)

Safety Data

• Hazardous Substances Data: 13436-49-2(Hazardous Substances Data)

Usage

General Description

1H-Indazole, 1-acetyl- (7CI,8CI,9CI) is a chemical compound belonging to the indazole class. It is an acetylated derivative of 1H-indazole, which is a heterocyclic compound with a bicyclic structure containing a five-membered ring fused to a six-membered ring. This particular derivative is characterized by the presence of an acetyl group attached to the indazole ring. It may have various applications in the field of chemistry, pharmaceuticals, and materials science, and its properties and potential uses are of interest to researchers and scientists. As with any chemical compound, proper handling and adherence to safety protocols are essential when working with 1H-Indazole, 1-acetyl- (7CI,8CI,9CI) to ensure safety and prevent any adverse effects.

InChI:InChI=1/C9H8N2O/c1-7(12)11-9-5-3-2-4-8(9)6-10-11/h2-6H,1H3

Upstream product

• 4838-00-0 2-methyl-2H-indazole 
• 507-02-8 acetyl iodide 
• 13436-50-5 2-Acetyl-indazol 
• 108-24-7 acetic anhydride 
• 614-68-6 2-tolyl isocyanate 
• 16466-61-8 1,2-bis(t-butyloxycarbonyl)hydrazine 
• 40138-16-7 2-formylbenzene boronic acid 
• 64-19-7 acetic acid 
• 271-44-3 benzimidazole 
• 75-36-5 acetyl chloride 
• 65782-99-2 benzoic acid-(N-nitroso-o-toluidide) 
• 98952-93-3 2-acetylamino-benzaldehyde-oxime 
• 13493-47-5 N-(2-formylphenyl)acetamide 
• 71-43-2 benzene 

Downstream Products

• 271-44-3 benzimidazole 
• 7788-69-4 1-phenyl-1H-indazole 
• 698-26-0 5-chloro-1H-indazole 
• 98083-43-3 1-Acetyl-5-chlorindazol 

Relevant articles and documents

Synthesis of indazoles from 2-formylphenylboronic acids

A method for the synthesis of indazoles was developed which involves a copper(ii) acetate catalysed reaction of 2-formylboronic acids with diazadicaboxylates followed by acid or base induced ring closure. Hydrazine dicarboxylates were also shown as competent reaction partners for the synthesis of indazoles, however, they required a stoichiometric amount of copper(ii) acetate for the C-N bond formation step. The transformation can be efficiently performed as a two step-one pot procedure to give a range of 1N-alkoxycarbonyl indazoles.

Copper-catalyzed C–N cross-coupling of arylboronic acids with N-acylpyrazoles

A copper-catalyzed C–N bond forming reaction of arylboronic acids and N-acylpyrazoles was developed. This procedure used N-acetyl protected pyrazoles as starting material instead of free pyrazoles (NH). The reaction worked under neutral conditions and did not require any base or ligand. The reaction showed good functional group tolerance.

Enzymic synthesis and biochemical activity of various indazole adenine dinucleotides

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