7788-69-4

Basic information

• Product Name: 1-PHENYL-1H-INDAZOLE
• Synonyms: 1-PHENYL-1H-INDAZOLE;1H-Indazole, 1-phenyl
• CAS NO: 7788-69-4
• Molecular Formula: C₁₃H₁₀N₂
• Molecular Weight: 194.2319
• Mol File: 7788-69-4.mol
• Article Data: 43

Chemical Properties

• Boiling Point: 275.9°C at 760 mmHg
• Flash Point: 120.7°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.00495mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-PHENYL-1H-INDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1H-INDAZOLE(7788-69-4)
• EPA Substance Registry System: 1-PHENYL-1H-INDAZOLE(7788-69-4)

Safety Data

• Hazardous Substances Data: 7788-69-4(Hazardous Substances Data)

Usage

General Description

1-PHENYL-1H-INDAZOLE is a chemical compound with the molecular formula C14H10N2. It is an indazole derivative commonly used in organic synthesis and research. 1-PHENYL-1H-INDAZOLE has a phenyl group attached to the indazole ring, giving it unique chemical and physical properties. It has been studied for its potential pharmacological properties, including its effects on the central nervous system. 1-PHENYL-1H-INDAZOLE has also demonstrated potential as a building block for the synthesis of various pharmaceuticals and organic compounds. Overall, this chemical compound has a wide range of applications in research and development in the fields of chemistry and pharmacology.

InChI:InChI=1/C13H10N2/c1-2-7-12(8-3-1)15-13-9-5-4-6-11(13)10-14-15/h1-10H

Upstream product

• 271-44-3 benzimidazole 
• 28899-97-0 triphenylbismuth(V) diacetate 
• 934-56-5 trimethyl(phenyl)stannane 
• 35713-98-5 2-iodo-benzaldehyde phenylhydrazone 
• 100-63-0 phenylhydrazine 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 98-80-6 phenylboronic acid 
• 66950-63-8 phenyl N,N-dimethylsulfamate 
• 65009-00-9 O-phenyl N,N-diethylcarbamate 
• 108-95-2 phenol 
• 108-86-1 bromobenzene 
• 13436-49-2 1-acetylindazole 
• 66003-76-7 Diphenyliodonium triflate 
• 62-53-3 aniline 

Downstream Products

• 1078735-62-2 1-[(1,1'-biphenyl)-2-yl]-1H-indazole 
• 7765-65-3 1-phenyl-3-(pyridin-3-yl)-1H-indazole 
• 1575-25-3 1,3-diphenyl-1H-indazole 
• 1394164-17-0 1-phenyl-3-(o-tolyl)-1H-indazole 
• 51112-92-6 3-(4-chlorophenyl)-1-phenyl-1H-indazole 
• 1394164-18-1 1-phenyl-3-(m-tolyl)-1H-indazole 
• 1394164-19-2 1‐phenyl‐3‐(p‐tolyl)‐1H‐indazole 
• 1394164-20-5 1-phenyl-3-(4-(trifluoromethyl)phenyl)-1H-indazole 
• 17583-00-5 2-phenylaminobenzonitrile 
• 323195-51-3 3-iodo-1-phenyl-1H-indazole 
• 1632155-75-9 methyl 2-(1H-indazol-1-yl)benzoate 
• 957-94-8 2-(1H-indazol-1-yl)benzoic acid 

Relevant articles and documents

Oxidant-Switched Palladium-Catalyzed Regioselective Mono- versus Bis-ortho-Aroylation of 1-Aryl-1H-indazoles with Aldehydes via C–H Bond Activation

A highly efficient oxidant-switched palladium-catalyzed regioselective C(sp2)–H/C(sp2)–H cross-dehydrogenative coupling (CDC) for direct mono/bis-ortho-aroylation of substituted 1-phenyl-1H-indazoles 1a–j with v

Direct Formation of 2-Substituted 2 H-Indazoles by a Pd-Catalyzed Reaction between 2-Halobenzyl Halides and Arylhydrazines

A direct and operationally simple method for the regioselective synthesis of 2-aryl-substituted 2H-indazoles is reported. The Pd-catalyzed reaction between easily available 2-bromobenzyl bromides and arylhydrazines employing Cs2CO3 as the base and t-Bu3PHBF4 as the ligand in DMSO at 120 °C in a sealed tube delivers the 2-substituted-2H-indazoles in a single synthetic step with yields up to 79%. The new method is based on a regioselective intermolecular N-benzylation followed by intramolecular N-arylation and oxidation.

N -Arylation of (hetero)arylamines using aryl sulfamates and carbamates via C-O bond activation enabled by a reusable and durable nickel(0) catalyst

An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst. This new stable catalyst was prepared on Fe3O4@SiO2 modified by EDTA and investigated by FT-IR, EDX, TEM, XRD, DLS, FE-SEM, XPS, NMR, TGA, VSM, ICP and elemental analysis techniques. The reaction proceeded via carbon-oxygen bond cleavage of (hetero)aryl carbamates and sulfamates under simple and mild conditions without the use of any external ligands. This method demonstrated functional group tolerance in the N-arylation of various nitrogen-containing compounds as well as aliphatic amines, anilines, pyrroles, pyrazoles, imidazoles, indoles, and indazoles with good to excellent yields. Furthermore, the catalyst could be easily recovered by using an external magnetic field and directly reused at least six times without notable reduction in its activity. This journal is