134441-93-3

Basic information

• Product Name: (S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: (S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester;(S)-1-BOC-2-PIPERIDINEMETHANOL;(S)-N-TERT-BUTYLOXYCARBONYL-2-(HYDROXYMETHYL)PIPERIDINE;(S)-TERT-BUTYL 2-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;(S)-N-Boc-piperidine-2-methanol;tert-Butyl (2S)-2-(hydroxymethyl)piperidine-1-carboxylate;(S)-tert-butyl 2-(hydroxyMethyl)piperidin-1-carboxylate;tert-Butyl (S)-2-(hydroxymethyl)piperidine-1-carboxylate
• CAS NO: 134441-93-3
• Molecular Formula: C₁₁H₂₁NO₃
• Molecular Weight: 215.29
• Product Categories: pharmacetical
• Mol File: 134441-93-3.mol
• Article Data: 24

Chemical Properties

• Melting Point: 73-75 °C
• Boiling Point: 308°C at 760 mmHg
• Flash Point: 140.1°C
• Appearance: /
• Density: 1.059
• Vapor Pressure: 6.41E-05mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: 2-8°C
• PKA: 15.08±0.10(Predicted)
• CAS DataBase Reference: (S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester(134441-93-3)
• EPA Substance Registry System: (S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester(134441-93-3)

Safety Data

• Hazardous Substances Data: 134441-93-3(Hazardous Substances Data)

Usage

General Description

(S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester is a chemical compound that belongs to the class of piperidine carboxylic acid esters. It is a chiral compound with a molecular formula of C11H21NO3 and a molecular weight of 215.29 g/mol. (S)-2-Hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester is often used as a reagent in organic synthesis and pharmaceutical research. The tert-butyl ester group provides stability to the molecule and protects the carboxylic acid functionality, making it useful for various synthetic transformations. Additionally, the presence of the hydroxymethyl and piperidine moieties makes this compound a valuable building block for the construction of bioactive molecules and pharmaceutical intermediates.

InChI:InChI=1/C11H21NO3/c1-11(2,3)15-10(14)12-7-5-4-6-9(12)8-13/h9,13H,4-8H2,1-3H3/t9-/m0/s1

Upstream product

• 157634-00-9 tert-butyl 2-(hydroxymethyl)piperidine-1-carboxylate 
• 3105-95-1 pipecolinic acid 
• 150521-32-7 (S)-1-N-Boc-piperidine-2-al 
• 1201635-96-2 (S)-tert-butyl-6-(benzyloxymethyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 116611-45-1 (2R)-2-t-butoxycarbonylamino-3-phenylsulfonyl-1-(2-tetrahydropyranyloxy)propane 
• 3433-37-2 piperidin-2-ylmethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 259133-67-0 2-carboxy-N-Boc-1,4,5,6-tetrahydropyridine 
• 146337-23-7 tert-butyl 3-methoxypiperidine-1-carboxylate 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 86953-81-3 tert-butyl 2-hydroxypiperidine-1-carboxylate 
• 131667-57-7 tert-butyl 1,2,3,4-tetrahydro-1-pyridinecarboxylate 
• 85275-45-2 N-tert-butoxycarbonyl-3-piperidinol 
• 675-20-7 piperidin-2-one 

Downstream Products

• 1214914-34-7 (S)-2-(2-oxo-propyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 3105-95-1 pipecolinic acid 
• 639458-43-8 (S)-2-(2-oxo-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 929917-69-1 (S)-(+)-piperidine-2-methanol hydrochloride 
• 139894-04-5 hexahydro-indolizin-3-one 
• 18881-13-5 (+)-coniceine 
• 259133-72-7 (2R,6R)-2-Phenoxythiocarbonyloxymethyl-6-propyl-piperidine-1-carboxylic acid tert-butyl ester 
• 393827-07-1 (S)-2-vinyl-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

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