134527-83-6

Basic information

• Product Name: 1(R)-<3-(tert-butyloxycarbonyl)-4(S)-(cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-2(S)-isopropyl-1,3-propanediol
• Synonyms: 1(R)-<3-(tert-butyloxycarbonyl)-4(S)-(cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-2(S)-isopropyl-1,3-propanediol
• CAS NO: 134527-83-6
• Molecular Weight: 413.598
• Mol File: 134527-83-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(R)-<3-(tert-butyloxycarbonyl)-4(S)-(cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-2(S)-isopropyl-1,3-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 1(R)-<3-(tert-butyloxycarbonyl)-4(S)-(cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-2(S)-isopropyl-1,3-propanediol(134527-83-6)
• EPA Substance Registry System: 1(R)-<3-(tert-butyloxycarbonyl)-4(S)-(cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-2(S)-isopropyl-1,3-propanediol(134527-83-6)

Safety Data

• Hazardous Substances Data: 134527-83-6(Hazardous Substances Data)

Upstream product

• 112190-42-8 3-<3(R)-<3-(tert-butyloxycarbonyl)-4(S)-cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-3-hydroxy-2(R)-isopropyl-1-oxopropyl>-4(R)-methyl-5(S)-phenyl-2-oxazolidinone 
• 107599-99-5 (4R,5S)-(+)-3-[3-methyl-1-oxobut-1-yl]-4-methyl-5-phenyl-2-oxazolidinone 
• 117997-58-7 tert-butyl (4S,5R)-4-(cyclohexylmethyl)-5-formyl-2,2-dimethyl-3-oxazolidinecarboxylate 

Downstream Products

• 112190-24-6 (2R,3R,4R,5S)-6-Cyclohexyl-3,4-dihydroxy-5-{(S)-3-(1H-imidazol-4-yl)-2-[2-(naphthalen-1-yloxy)-acetylamino]-propionylamino}-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 134458-76-7 (2R,3R,4R,5S)-6-Cyclohexyl-3,4-dihydroxy-5-[(S)-3-(1H-imidazol-4-yl)-2-(2-phenoxy-acetylamino)-propionylamino]-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 134458-78-9 (2R,3R,4R,5S)-5-[(S)-2-(2-Amino-acetylamino)-3-(1H-imidazol-4-yl)-propionylamino]-6-cyclohexyl-3,4-dihydroxy-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 134458-77-8 (2R,3R,4R,5S)-6-Cyclohexyl-3,4-dihydroxy-5-[(S)-2-(2-hydroxy-acetylamino)-3-(1H-imidazol-4-yl)-propionylamino]-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 134458-79-0 (2R,3R,4R,5S)-6-Cyclohexyl-5-(2-cyclohexyl-acetylamino)-3,4-dihydroxy-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 146394-88-9 (2R,3R,4R,5S)-5-Amino-6-cyclohexyl-3,4-dihydroxy-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 112190-45-1 2(R)-<5(R)-<1(S)-<(tert-butyloxycarbonyl)amino>-2-cyclohexylethyl>-2,2-dimethyl-4(R)-dioxolanyl>-3-methylbutanoic acid 
• 134527-84-7 2(S)-<5(R)-<1(S)-<(tert-butyloxycarbonyl)amino>-2-cyclohexylethyl>-2,2-dimethyl-4(R)-dioxolanyl>-3-methylbutanol 

Relevant articles and documents

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The peptidomimetic template and the dihydroxyethylene isostere insert that were applied successfully to the design of renin inhibitors have been extended to the related protease from human immunodeficiency virus (HIV).The present report describes the stru