1346015-58-4

Basic information

• Product Name: N-butyl-5,7-dimethoxy-2-phenylquinoline-4-amine
• CAS NO: 1346015-58-4
• Molecular Weight: 336.434
• Mol File: 1346015-58-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-butyl-5,7-dimethoxy-2-phenylquinoline-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-butyl-5,7-dimethoxy-2-phenylquinoline-4-amine(1346015-58-4)
• EPA Substance Registry System: N-butyl-5,7-dimethoxy-2-phenylquinoline-4-amine(1346015-58-4)

Safety Data

• Hazardous Substances Data: 1346015-58-4(Hazardous Substances Data)

Upstream product

• 159188-33-7 5,7-dimethoxy-2-phenylquinoline-4(1H)-one 
• 380501-39-3 N-(2-acetyl-3,5-dimethoxy-phenyl)-benzamide 
• 94088-74-1 N-(3,5-dimethoxyphenyl)benzamide 
• 10272-07-8 3.5-dimethoxyaniline 
• 98-88-4 benzoyl chloride 
• 1156271-96-3 4-chloro-5,7-dimethoxy-2-phenylquinoline 
• 109-73-9 N-butylamine 

Relevant articles and documents

Synthesis and antitumor activity of novel 4-aminoquinoline derivatives

A series of novel 4-aminoquinoline derivatives were synthesized as antitumor agents by reacting 4-chloroquinoline with the corresponding mono/dialkyl amines. The cytotoxicity of these compounds was evaluated in vitro against HCT-116, A549, DU-145, HepG2, and LN229 cell lines. The results showed that most of the synthesized compounds displayed excellent cytotoxicity, and 5,7-dimethoxy-2-phenyl-N-propylquinoline-4-amine (6a) displayed the most potent cytotoxicity against HCT-116 cells. Furthermore, 6a could decrease VEGF protein expression.