1346137-01-6Relevant articles and documents
Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4
Li, Cong,Deng, Xiaobing,Zhang, Weilin,Xie, Xiaowen,Conrad, Marcus,Liu, Ying,Angeli, José Pedro Friedmann,Lai, Luhua
, p. 266 - 275 (2019)
Glutathione peroxidase 4 (GPX4) is essential for cell membrane repair, inflammation suppression, and ferroptosis inhibition. GPX4 upregulation provides unique drug discovery opportunities for inflammation and ferroptosis-related diseases. However, rationa
Design and synthesis of a highly efficient labelling reagent for incorporation of tetrafluorinated aromatic azide into proteins
Ma, Dejun,Kang, Xueying,Gao, Yasi,Zhu, Jiqin,Yi, Long,Xi, Zhen
, p. 888 - 893 (2019/01/10)
Chemical labelling can significantly extend the structures and functions of proteins for advanced applications. Herein, a highly efficient bench-stable reagent diazo-azide was designed and synthesized for the incorporation of tetrafluorinated aromatic azi