1346175-23-2Relevant articles and documents
A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors
Selig, Roland,Goettert, Marcia,Schattel, Verena,Schollmeyer, Dieter,Albrecht, Wolfgang,Laufer, Stefan
, p. 8429 - 8439 (2013/01/15)
In this study we report the design, synthesis, and biological evaluation of constrained aminopyridinylimidazoles as p38α MAP kinase inhibitors. The frozen analogue approach focused on the pyridinyl unit, using purine bioisosteres as constrained structure