1346175-23-2

Upstream product

• 1401083-50-8 C₂₉H₄₁FN₂OSn 
• 744209-63-0 1-(benzenesulfonyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine 
• 1213269-68-1 4-(4-fluorophenyl)-1-(methoxymethyl)-2-phenyl-1H-imidazole 
• 100-52-7 benzaldehyde 
• 403-32-7 (4-fluorophenyl)glyoxal 
• 889939-25-7 1-(benzenesulfonyl)-4-bromo-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors

In this study we report the design, synthesis, and biological evaluation of constrained aminopyridinylimidazoles as p38α MAP kinase inhibitors. The frozen analogue approach focused on the pyridinyl unit, using purine bioisosteres as constrained structure

The application of Stille cross-coupling reactions with multiple nitrogen containing heterocycles

Substituted imidazoles and purine bioisosteres have been widely studied in the literature. We endeavored to combine these heterocyclic core structures into precursors, especially 7-azaindoles, of previously unknown pharmacologically relevant lead structur