134755-22-9Relevant academic research and scientific papers
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach
Wu, Yu-Shan,Coumar, Mohane Selvaraj,Chang, Jang-Yang,Sun, Hsu-Yi,Kuo, Fu-Ming,Kuo, Ching-Chuan,Chen, Ying-Jun,Chang, Chi-Yen,Hsiao, Chia-Ling,Liou, Jing-Ping,Chen, Ching-Ping,Yao, Hsien-Tsung,Chiang, Yi-Kun,Tan, Uan-Kang,Chen, Chiung-Tong,Chu, Chang-Ying,Wu, Su-Ying,Yeh, Teng-Kuang,Lin, Chin-Yu,Hsieh, Hsing-Pang
scheme or table, p. 4941 - 4945 (2010/03/02)
BPR0L075 (2) is a potential anticancer drug candidate designed from Combretastatin A-4 (1) based on the bioisosterismprinciple.Metabolites of 2, proposed from in vitrohumanmicrosome studies,were synthesized, leading to the identification of metabolite-der
Total synthesis of discorhabdin C: A general aza spiro dienone formation from O-silylated phenol derivatives using a hypervalent iodine reagent
Kita, Yasuyuki,Tohma, Hirofumi,Inagaki, Masanao,Hatanaka, Kenji,Yakura, Takayuki
, p. 2175 - 2180 (2007/10/02)
Hypervalent iodine oxidation of O-silylated phenols bearing various types of aminoquinones at the para position in 2,2,2-trifluoroethanol gave azacarbocyclic spiro dienones in good yields. Using this method, the first total synthesis of discorhabdin C, wh
Hypervalent iodine oxidation of O-silylated phenol derivatives to azacarbocyclic spirodienones; synthetic approach to the anticancer marine alkaloid, discorhabdin C
Kita,Tohma,Inagaki,Hatanaka,Kikuchi,Yakura
, p. 2035 - 2038 (2007/10/02)
Hypervalent iodine oxidation of O-silylated phenols bearing various types of aminoquinones at the p-position in 2,2,2-trifluoroethanol gave azacarbocyclic spirodienones in good yields and application of this reaction to the synthetic approach to discorhab
