1347654-89-0Relevant academic research and scientific papers
Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase
Ma, Kaiqing,Wang, Penghui,Fu, Wei,Wan, Xiaolong,Zhou, Lu,Chu, Yong,Ye, Deyong
, p. 6724 - 6727 (2011/12/21)
HIV-1 integrase is an essential enzyme for viral replication and a validated target for the development of drugs against AIDS. With an aim to discover new potent inhibitors of HIV-1 integrase, we developed a pharmacophore model based on reported inhibitor
