1347739-89-2

Upstream product

• 96721-65-2 C₁₆H₁₈NO₃P 
• 110470-33-2 dimethyl α-aminobenzyl phosphonate 
• 110284-78-1 2-(4',6'-dimethoxypyrimidine-2'-yl)oxy-benzoic acid 
• 100-52-7 benzaldehyde 
• 113583-35-0 4,6-dimethoxypyrimidin-2-yl methyl sulfone 
• 92-29-5 hydrobenzamide 
• 110284-90-7 methyl 2-(4',6'-dimethoxypyrimidine-2'-yl)oxybenzoate 
• 119-36-8 methyl salicylate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel phosphonates derivatives of as potential antitumor agents

A series of dialkyl [2-(4,6-dimethoxypyrimidin-2-yloxy)benzamido](aryl) methylphosphonates derivatives were designed and synthesized. All the new compounds were identified by elemental analysis, IR, 1H NMR, 31P NMR, and MS. Their antitumor activity against KB and CNE1 cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further study of structure modification. In particular, the compounds 6i and 6j displayed more potent cytotoxic activities against KB in comparison with 5-FU. Copyright Taylor & Francis Group, LLC.