134856-46-5Relevant articles and documents
Enantioselective Aluminum-Free Alkene Hydroarylations through C?H Activation by a Chiral Nickel/JoSPOphos Manifold
Loup, Joachim,Müller, Valentin,Ghorai, Debasish,Ackermann, Lutz
, p. 1749 - 1753 (2019)
Highly enantioselective nickel-catalyzed alkene endo-hydroarylations were accomplished with full selectivity by organometallic C?H activation. The asymmetric assembly of chiral six-membered scaffolds proved viable in the absence of pyrophoric organoaluminum reagents within an unprecedented nickel/JoSPOphos manifold.
Microwave-assisted C-H bond activation: A rapid entry into functionalized heterocycles
Tan, Kian L.,Vasudevan, Anil,Bergman, Robert G.,Ellman, Jonathan A.,Souers, Andrew J.
, p. 2131 - 2134 (2007/10/03)
(Matrix presented) Microwave irradiation strongly accelerates the rhodium-catalyzed intramolecular coupling of a benzimidazole C-H bond to pendant alkenes. The cyclic products were formed in moderate to excellent yields with reaction times less than 20 min. Additionally, the use of microwave irradiation allowed the reactions to be performed without any solvent purification and with minimal precautions to exclude air.
Synthesis of Benzimidazoles Containing a Fused Alicyclic Ring By Rhodium - Catalysed Hydroformylation of N-Alkenyl-1,2-diaminobenzenes
Anastasiou, Despina,Campi, Eva M.,Chaouk, Hassan,Jackson, W. Roy
, p. 7467 - 7478 (2007/10/02)
Rhodium-catalysed reactions of N-alkenyl-1,2-diaminobenzenes (3) with hydrogen and carbon monoxide give benzimidazoles containing a fused alicyclic ring ((8) and (9)) in excellent yields.In some cases intermediate bicyclic compounds can be isolated and the 1H and 13C n.m.r. spectra of one of these, the 3,4,5,6-tetrahydro-4-methyl-3H-1,6-benzodiazocine (6), shows evidence for unusual atropisomerism.
