134886-28-5

Upstream product

• 591-87-7 Allyl acetate 
• 201230-82-2 carbon monoxide 
• 286376-23-6 4-methyl-N-(prop-1-yn-1-yl)benzenesulfonamide 
• 104-55-2 3-phenyl-propenal 
• 161374-29-4 N-allyl-N-but-2-ynyl-4-methyl-benzenesulfonamide 
• 64609-15-0 2,3,5-tri-O-acetyl-D-xylofuranose 
• 133886-40-5 N-tosyl-N-allylpropargylamine 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 104-54-1 3-Phenylpropenol 
• 123-73-9 crotonaldehyde 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 

Relevant academic research and scientific papers

Catalytic Pauson-Khand Reaction in Ethylene Glycol-Toluene: Activity, Selectivity, and Catalyst Recycling

The use of ethylene glycol (15% v/v in toluene) as additive in the catalytic Pauson-Khand reaction (PKR) is reported. In most cases both the yield and selectivity were enhanced compared to standard protocols. Moreover, the immiscibility of ethylene glycol

A catalytic scalable Pauson-Khand reaction in a plug flow reactor

A catalytic, scalable intra- and intermolecular Pauson-Khand reaction protocol using generally 5 mol% of Co2(CO)8 as the catalyst in a plug flow reactor (PFR) is shown.

Pauson-Khand reactions in a photochemical flow microreactor

Pauson-Khand reactions were achieved at ambient temperature without any additive using a photochemical flow microreactor. The efficiency of the reaction was better than that in a conventional batch reactor, and the reaction could be operated continuously for 1 h.

Rh(I)-catalyzed cyclocarbonylation of enynes with glyceraldehyde: An available carbonyl source derived from sugar alcohols

Catalytic cyclocarbonylation reactions using a glyceraldehyde derivative as a carbonyl source are described. The rhodium(I)-catalyzed reaction of enynes with glyceraldehyde acetonide gave bicyclic cyclopentenones as the products. This presents an interesting use of a sugar alcohol derived carbon resource as well as a convenient procedure for the cyclocarbonylation of enynes. Georg Thieme Verlag Stuttgart · New York.

Utilization of aldoses as a carbonyl source in cyclocarbonylation of enynes

Figure presented. The reaction of enynes with acetyl-masked aldoses in the presence of a rhodium(I) catalyst resulted in cyclocarbonylation, thus avoiding the direct use of carbon monoxide, to afford bicyclic cyclopentenones. In rhodium catalysis, aldoses serve as a carbon monoxide equivalent by donating their carbonyl moieties on the acyclic aldehyde form to enynes. A variety of aldoses, including d-glucose, d-mannose, d-galactose, d-xylose, and d-ribose, can be used as a carbonyl source. Using the method, a wide variety of enynes were cyclocarbonylated in 22-67% yields. An asymmetric variant also proceeded with moderate to high enantioselectivity.

Rhodium-catalyzed pauson-khand-type reaction using alcohol as a source of carbon monoxide

Three in one pot! Bicyclic cyclopentenones have been synthesized from enynes in alcohol in the presence of a rhodium catalyst through a newly developed auto-tandem catalytic reaction. This process combines three mechanistically distinctive reactions - an

Microwave-assisted rhodium-complex-catalyzed cascade decarbonylation and asymmetric Pauson-Khand-type cyclizations

Microwave-assisted Rh-diphosphane-complex-catalyzed dual catalysis is reported. This cooperative process provides [2+2+1] cycloadducts by sequential decarbonylation of aldehyde or formate and carbonylation of enynes within a short period of time. Various

Effect of lithium chloride on tuning the reactivity of Pauson-Khand reactions catalyzed by palladium-tetramethylthiourea

A general and robust transition-metal-catalyzed Pauson-Khand reaction is still difficult to achieve. In this contribution, we describe our recent observations on the effect of lithium chloride on Pauson-Khand reactions catalyzed by palladium(II) chloride-

Immobilized Co/Rh heterobimetallic nanoparticle-catalyzed Pauson-Khand-type reaction

Co/Rh heterobimetallic nanoparticles were prepared from cobalt-rhodium carbonyl clusters [Co2Rh2(CO)12 and Co 3Rh(CO)12] and immobilized on charcoal. HR-TEM revealed that the size of the heterobimetal

Tetramethyl thiourea/Co2(CO)8-catalyzed Pauson-Khand reaction under balloon pressure of CO

(Chemical Equation Presented) A Pauson-Khand type of conversion of enynes to bicyclic cyclopentenones employing the commercially available Co 2(CO)8 and tetramethylthiourea (TMTU) as catalysts is described. This method allows a varie