13491-16-2

Upstream product

• 93233-47-7 ((R)-1-tert-Butyl-4,4-dimethyl-pent-2-ynyl)-benzene 
• 27854-88-2 (R)-1-(4-pyridinyl)ethanol 
• 88549-56-8 C₂₄H₃₀O₃ 
• 124-38-9 carbon dioxide 
• 1688-17-1 1-chloro-2,2-dimethyl-1-phenylpropane 
• 217321-19-2 {(R)-1-[(2S,5R)-2-Isopropyl-5-methyl-cyclohex-(E)-ylidenemethyl]-2,2-dimethyl-propyl}-benzene 
• 93233-53-5 (R)-2,2,6,6-Tetramethyl-5-phenyl-heptane-3,4-dione 
• 93233-50-2 ((R)-1-tert-Butyl-but-2-ynyl)-benzene 
• 13490-70-5 (+/-)-α-tert-butylphenylacetic acid 

Downstream Products

• 71214-37-4 (R)-3,3-Dimethyl-2-phenyl-butyric acid methyl ester 
• 23406-56-6 R-(+)-3,3-Dimethyl-2-phenyl-1-chlorbutan 
• 23406-54-4 S-(-)-2,2-Dimethyl-3-cyclohexylbutan 
• 19262-20-5 (1,2,2-Trimethyl-propyl)-benzene 
• 82323-53-3 (R)-(-)-1,1,2-triphenyl-3,3-dimethylbutanol 
• 100702-91-8 (R)-(-)-1,1,2-triphenyl-3,3-dimethylbutane 
• 82372-89-2 (R)-(-)-methyl α-tert-butylphenylacetate 
• 33124-21-9 (R)-3,3-Dimethyl-2-phenyl-1-butanol 
• 23406-58-8 (R)-(-)-4,4-dimethyl-3-phenylpentan-2-one 

Relevant academic research and scientific papers

Chiral α-substituted carbonyls and alcohols from the S(N)2' displacement of cuprates on chiral carbonates: An alternative to the alkylation of chiral enolates

A highly stereoselective sequence of reactions, based on the anti-selective S(N)2' addition of cuprates to allylic carbonates, transforms alkynes or alkenyl halides into carbonyls having α-chiral centers. The method, which uses menthone as a chiral auxiliary, is a useful alternative to the alkylation of chiral enolates with the added advantage of allowing for the 'alkylation' of sec- and tert-alkyl and aryl groups.

STEREOCHEMISTRY OF THE SN2' DISPLACEMENT OF CHIRAL 1,3-DISUBSTITUTED BROMOALLENES TO FORM CHIRAL ACETYLENES

Optically active 1,3-disubstituted bromoallenes react with a variety of cuprate reagents preferentially is an SN2' fashion with very high anti selectivity.

Configuration Determination of (R)-(-)-1,1,2-Triphenyl-3,3-dimethylbutane and the Stereochemistry of the Reaction of Benzhydryllithium with (R)-(+)-α-Phenylneopentyl Chloride

A three-step synthesis of optically pure (R)-(-)-1,1,2-triphenyl-3,3-dimethylbutane from (R)-(-)-α-tert-butylphenylacetic acid has been accomplished.The synthesis of α-phenylneopentyl chloroformate from optically pure (R)-(+)-1-phenyl-2,2-dimethyl-1-propa