Tetrahedron p. 15067 - 15070 (1999)
Update date:2022-08-16
Topics:
Goodman, Allan J.
Stanforth, Stephen P.
Tarbit, Brian
3,6-Dichloropyridizine 1a was converted in good yield into its mono-iodo derivative 1b when treated with a mixture of hydriodic acid and sodium iodide. Pure samples of the mono-iodo derivatives 2b, 3b and 4b could not be obtained from their corresponding dichlorinated precursors with these reagents. Compounds 1b and 4b underwent palladium catalysed Suzuki, Sonogashira and other coupling reactions.
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