1350751-87-9

Upstream product

• 78604-82-7 α-p-toluidino-deoxybenzoin 
• 109-77-3 malononitrile 
• 106-49-0 p-toluidine 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Downstream Products

• 1350751-89-1 7-(4-methylphenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one 
• 1350751-91-5 7-(4-methylphenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-thione 
• 1350751-93-7 (7-(4-methylphenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-hydrazine 
• 1350751-95-9 7-(4-methylphenyl)-8,9-diphenyl-7H-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine-3-thione 
• 1350751-96-0 7-(4-methylphenyl)-8,9-diphenyl-7H-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine 
• 1350751-97-1 3-methyl-7-(4-methylphenyl)-8,9-diphenyl-7H-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine 
• 1350751-94-8 N-benzylidene-N'-(7-(4-methylphenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-hydrazine 
• 1350751-90-4 4-chloro-7-(4-methylphenyl)-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidine 

Relevant academic research and scientific papers

Pyrrolopyrazoles: Synthesis, evaluation and pharmacological screening as antidepressant agents

Background: Pyrroles and fused pyrroles are of great interest as biologically active compounds, among these activities; antidepressant activity is of special concern. Objective: Synthesis of a series of pyrrolopyrazoles and their pyrimidine derivatives an

Synthesis and lung cancer cell line study of pyrrolo[2,3-d]pyrimidine analogs

Three series of new pyrrolo[2,3-d]pyrimidines having diverse groups at position C4 and N7 of the pyrrolo[2,3-d]pyrimidine core were synthesized and their cell line study on the National Cancer Institute (NCI) H1 299 lung cancer cell line was performed. The details of the synthetic methods and characterization data of the synthesized compounds have been presented in this study. Compounds 08a, 08h, 08j, 09h, 09i, 09j, 09m, 09n, and 09o showed excellent anticancer activity compared to standard doxorubicin half maximal inhibitory concentration value on NCI H1 299 (lung cancer cell line) which was nontoxic to normal Vero cell line.

Novel antiviral compounds against gastroenteric viral infections

Viral gastroenteritis is a serious viral infection which affects a large number of individuals around the world, most of them being children. The infection may occur due to different viruses, for example, coxsackievirus, adenovirus, and rotavirus. There i

Synthesis and kinetic testing of new inhibitors for a metallo-β- lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa

There are currently no clinically useful inhibitors against metallo-β-lactamases (MBLs), enzymes that confer resistance against a broad spectrum of commonly used antibiotics and that are produced by an increasing number of bacterial pathogens. New pyrrole