1350751-96-0Relevant academic research and scientific papers
Evaluation of the anti-inflammatory activity of some pyrrolo[2,3-d] pyrimidine derivatives
Mohamed, Mosaad S.,Kamel, Rehab,Abd El-Hameed, Rania H.
, p. 2244 - 2252 (2013/07/26)
A series of novel pyrrolo[2,3-d]pyrimidine and fused pyrrolo[2,3-d] pyrimidine derivatives were synthesized and their structures were characterized by elemental analysis, 1H NMR, IR, and mass spectroscopy. Their in vivo anti-inflammatory activi
Synthesis and kinetic testing of new inhibitors for a metallo-β- lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa
Mohamed, Mosaad S.,Hussein, Waleed M.,McGeary, Ross P.,Vella, Peter,Schenk, Gerhard,Abd El-Hameed, Rania H.
experimental part, p. 6075 - 6082 (2011/12/22)
There are currently no clinically useful inhibitors against metallo-β-lactamases (MBLs), enzymes that confer resistance against a broad spectrum of commonly used antibiotics and that are produced by an increasing number of bacterial pathogens. New pyrrole
