1351708-13-8Relevant articles and documents
Rhodium-Catalyzed Enantioselective Addition of Arylboroxines to Isatin-Derived N-Boc Ketimines Using Chiral Phosphite-Olefin Ligands: Asymmetric Synthesis of 3-Aryl-3-amino-2-oxindoles
Yu, Yue-Na,Qi, Wei-Yi,Wu, Chun-Yan,Xu, Ming-Hua
, p. 7493 - 7497 (2019)
An efficient rhodium-catalyzed enantioselective arylation of isatin-derived N-Boc ketimines with arylboroxines has been developed using H8-BINOL-derived phosphite-olefin as a chiral ligand. This method allows access to a broad variety of valuab
Bifunctional thiourea-modified polymers of intrinsic microporosity for enantioselective α-amination of 3-aryl-2-oxindoles in batch and flow conditions
Andrés, José M.,Maestro, Alicia,Martín, Laura,Pedrosa, Rafael
, p. 9275 - 9283 (2020/12/03)
Two novel polymers of intrinsic microporosity decorated with chiral thioureas have been used as recoverable organocatalysts in enantioselective α-amination of 3-aryl-substituted oxindoles, creating a quaternary stereocenter. Both catalysts were able to pr
Asymmetric organocatalytic α-amination of 2-oxindoles with bis(2,2,2-trichloroethyl)azo-dicarboxylate
Bondanza, Mattia,Pescitelli, Gennaro,Mandoli, Alessandro
, p. 2590 - 2594 (2018/05/29)
An enantioselective electrophilic amination of 3-substituted-2-oxindoles is reported, using bis(2,2,2-trichloroethyl)azo-dicarboxylate and commercially available Cinchona alkaloid organocatalysts. The best results were obtained in the reaction of 3-aryl s
Organocatalytic asymmetric α-amination of unprotected 3-aryl and 3-aliphatic substituted oxindoles using di-tert-butyl azodicarboxylate
Zhou, Feng,Ding, Miao,Liu, Yun-Lin,Wang, Cui-Hong,Ji, Cong-Bin,Zhang, Yi-Yu,Zhou, Jian
supporting information; experimental part, p. 2945 - 2952 (2012/01/02)
The bifunctional quinine-derived thiourea catalyst 14 was found to catalyze the direct amination of unprotected 3-aryl and aliphatic substituted oxindoles with di-tert-butyl azodicarboxylate (DBAD) to construct a tetrasubstituted stereogenic carbon center at the C-3 position of oxindoles in good to excellent yield and enantioselectivity. Copyright