13518-80-4 Usage
General Description
2-Trimethylsilyl-1,2,3-triazole is a chemical compound that is commonly used as a reagent in organic synthesis. It is characterized by its three nitrogen atoms in a five-membered ring, which makes it a versatile building block for various reactions. 2-TRIMETHYLSILYL-1,2,3-TRIAZOLE is often utilized as a protecting group for alcohols and amines due to its stability and ease of removal under mild conditions. Additionally, it can be used in the synthesis of pharmaceuticals and agrochemicals, as well as in the modification of natural products. Its unique structure and reactivity make it a valuable tool in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 13518-80-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,1 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13518-80:
(7*1)+(6*3)+(5*5)+(4*1)+(3*8)+(2*8)+(1*0)=94
94 % 10 = 4
So 13518-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H11N3Si/c1-9(2,3)8-6-4-5-7-8/h4-5H,1-3H3
13518-80-4Relevant articles and documents
Carbazole inhibitors of histamine receptors for the treatment of disease
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Page/Page column 47, (2012/01/04)
The present invention relates to carbazole compounds, pharmaceutical compositions comprising them, and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
Alkylation and acylation of the 1,2,3,triazole ring
Ohta, Shunsaku,Kawasaki, Ikuo,Uemura, Takahiro,Yamashita, Masayuki,Yoshioka, Tomomichi,Yamaguchi, Satoshi
, p. 1140 - 1145 (2007/10/03)
Trimethylsilylation of 1,2,3-triazole regioselectively proceeded to give 2-trimethylsilyl-2H-1,2,3-triazole, which was treated with primary alkyl halides in the presence of tetrabutylammonium fluoride to give 1-alkyl-1H- 1,2,3-triazoles as a Sole product 1-Methyl-5-substituted 1H-1,2,3-triazoles were prepared by alkylation of 5-lithio-1-methyl-1H-1,2,3-triazole, and 1- methyl-4-substituted 1H-1,2,3-triazoles were obtained by alkylation of 4- lithio-1-methyl-5-phenylthio-1H-1,2,3-triazole followed by reductive desulfurization.
