2845-85-4

Basic information

• Product Name: 4-chloroisophthalic acid
• Synonyms: 4-chloroisophthalic acid;4-Chloro-1,3-benzenedicarboxylic acid;4-Chlorobenzene-1,3-dicarboxylic acid;1,3-Benzenedicarboxylic acid, 4-chloro-;Isophthalic acid, 4-chloro-
• CAS NO: 2845-85-4
• Molecular Formula: C₈H₅ClO₄
• Molecular Weight: 200.58
• Mol File: 2845-85-4.mol

Chemical Properties

• Melting Point: >290 °C
• Boiling Point: 424.9°Cat760mmHg
• Flash Point: 210.8°C
• Appearance: /
• Density: 1.586g/cm³
• Vapor Pressure: 5.59E-08mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.51±0.25(Predicted)
• CAS DataBase Reference: 4-chloroisophthalic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloroisophthalic acid(2845-85-4)
• EPA Substance Registry System: 4-chloroisophthalic acid(2845-85-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2845-85-4(Hazardous Substances Data)

Usage

Uses

Used in Polymer Production:
4-chloroisophthalic acid is used as a monomer in the production of high-performance polyesters, enhancing the properties of the resulting materials due to its ability to modify their characteristics.
Used in Pharmaceutical and Agrochemical Synthesis:
4-chloroisophthalic acid is utilized as a key building block in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and effective compounds for medical and agricultural applications.
Used in Functional Materials Development:
In the field of materials science, 4-chloroisophthalic acid is employed in the development of functional materials such as liquid crystals, showcasing its versatility and importance in creating advanced materials with specific properties.
Used in Organic Synthesis as a Reagent:
4-chloroisophthalic acid also serves as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the synthesis of a wide range of organic compounds across different industries.

InChI:InChI=1/C8H5ClO4/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3H,(H,10,11)(H,12,13)

Upstream product

• 95-66-9 2,4-dimethylchlorobenzene 
• 73129-52-9 2'-chloro-5-methylacetophenone 
• 37074-39-8 4-chloro-3-methylacetophenone 
• 13520-08-6 1-chloro-2,4-bis-dichloromethyl-benzene 
• 2845-84-3 4-chloroisophthalaldehyde 
• 7446-70-0 aluminium trichloride 
• 122-01-0 4-chloro-benzoyl chloride 
• 10025-87-3 trichlorophosphate 
• 118-91-2 ortho-chlorobenzoic acid 
• 96576-98-6 (E)-1,4-bis(4-chloro-3-methylphenyl)-2-butene-1,4-dione 

Downstream Products

• 13519-90-9 2,4-dicyano-1-fluorobenzene 
• 4387-30-8 4-chloro-1,3-benzenedicarbonitrile 
• 13520-07-5 4-morpholinoisophthalonitrile 
• 41779-14-0 5-Benzylamino-N-methyl-4-phenoxy-isophthalamic acid 
• 41779-26-4 Aethyl-4-anilino-5-carboxy-3-nitro-benzoat 
• 41884-03-1 5-Benzylamino-N-(2-methoxy-ethyl)-4-phenoxy-isophthalamic acid 
• 41779-45-7 5-Benzylamino-4-(4-chloro-phenylsulfanyl)-isophthalic acid diethyl ester 
• 41779-16-2 5-Benzylamino-N-butyl-4-phenoxy-isophthalamic acid 
• 41779-42-4 5-Benzylamino-4-phenylsulfanyl-isophthalic acid diethyl ester 
• 41779-48-0 5-Benzylamino-4-phenoxy-isophthalic acid diethyl ester 
• 41779-09-3 5-Benzylamino-N-(2-hydroxy-ethyl)-4-phenylsulfanyl-isophthalamic acid 
• 41779-10-6 5-Benzylamino-4-(4-chloro-phenylsulfanyl)-isophthalic acid 3-ethyl ester 
• 41779-38-8 5-Benzylamino-N,N-dimethyl-4-phenylamino-isophthalamic acid ethyl ester 
• 41779-15-1 5-Benzylamino-4-phenoxy-N-propyl-isophthalamic acid 

Relevant articles and documents

Electrophilicity and nucleophilicity of commonly used aldehydes

The present approach for determining the electrophilicity (E) and nucleophilicity (N) of aldehydes includes a kinetic study of KMNO4 oxidation and NaBH4 reduction of aldehydes. A transition state analysis of the KMNO4 promoted aldehyde oxidation reaction has been performed, which shows a very good correlation with experimental results. The validity of the experimental method has been tested using the experimental activation parameters of the two reactions. The utility of the present approach is further demonstrated by the theoretical versus experimental relationship, which provides easy access to E and N values for various aldehydes and offers an at-a-glance assessment of the chemical reactivity of aldehydes in various reactions. the Partner Organisations 2014.