1351997-22-2

Upstream product

• 404010-35-1 N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide 
• 17341-93-4 2,2,2-Trichloroethyl chloroformate 
• 404010-33-9 N-(3-nitro-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide 
• 404010-31-7 5-tert-Butyl-2-methoxy-3-nitroaniline 
• 77055-30-2 5-tert-butyl-2-methoxy-1,3-dinitrobenzene 
• 5396-38-3 1-(tert-butyl)-4-methoxybenzene 

Downstream Products

• 1443240-97-8 N-(5-tert-butyl-2-methoxy-3-{3-[(1S,4R)-4-(3-piperidin-1-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-ureido}-phenyl)-methanesulfonamide 

Relevant academic research and scientific papers

Novel chromene diarylurea compounds, and preparation method and application thereof

The invention relates to compounds represented by the general formula I, or isomers, pharmaceutical salts and solvates thereof; the invention also relates to a composition containing the compounds represented by the general formula I, or the isomers, the

KINASE INHIBITORS

Compounds of formula (I) or a pharmaceutically acceptable salt thereof: formula (I) wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.