1353100-91-0

Basic information

• Product Name: 1-H-pyrazole-4-carboxylic acid,3-broMo,ethyl ester
• Synonyms: 1-H-pyrazole-4-carboxylic acid,3-broMo,ethyl ester;3-Bromo-4-(ethoxycarbonyl)-1H-pyrazole;3-broMo-1-H-pyrazole-4-carboxylic acid ethyl ester
• CAS NO: 1353100-91-0
• Molecular Formula: C₆H₇BrN₂O₂
• Molecular Weight: 219.03598
• Product Categories: 9.7g
• Mol File: 1353100-91-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 331.1±22.0 °C(Predicted)
• Appearance: /
• Density: 1.664±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.58±0.50(Predicted)
• CAS DataBase Reference: 1-H-pyrazole-4-carboxylic acid,3-broMo,ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-H-pyrazole-4-carboxylic acid,3-broMo,ethyl ester(1353100-91-0)
• EPA Substance Registry System: 1-H-pyrazole-4-carboxylic acid,3-broMo,ethyl ester(1353100-91-0)

Safety Data

• Hazardous Substances Data: 1353100-91-0(Hazardous Substances Data)

Usage

Uses

Ethyl 3-Bromo-1H-pyrazole-4-carboxylate can be used as plasma kallikrein inhibitors.

Upstream product

• 6994-25-8 3-amino-4-pyrazolecarboxylic acid ethyl ester 
• 1260243-04-6 ethyl 5-amino-1H-pyrazole-4-carboxylate 

Downstream Products

• 1355249-61-4 ethyl 3-bromo-1-(4-methoxybenzyl)-1H-pyrazole-4-carboxylate 
• 1355249-62-5 C₁₆H₁₈N₂O₃ 
• 116344-32-2 ethyl 1-methyl-5-phenyl-1H-pyrazole-4-carboxylate 
• 116344-31-1 ethyl 1-methyl-3-phenyl-1H-pyrazole-4-carboxylate 
• 105486-72-4 5-bromo-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 139308-52-4 ethyl 3-bromo-1-methyl-1H-pyrazole-4-carboxylate 

Relevant articles and documents

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

N1/N2-Lactam Acetyl-CoA carboxylase inhibitors

The invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein G is R1, R2 and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase enzyme(s) in an animal

TRICYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention describes and claims compounds of the Structural Formula I, Structural Formula II, or Structural Formula III: wherein R1, R2, R3 and R3' are -H or methyl, or R3 and R3 taken together form a double bond, or R3' is -H and R2 and R3 taken together form a spiro-cyclopropyl substituent, R4 is -H or -F, and R5 is -H, methyl, -CI or -Br, Formula II wherein R1 is -H, ethyl-, isopropyl-, cyclopropyl-, methyl- or methoxy-, R4 is -H or -F, and "Y" is: (a) -CH2-; (b) -CR6H-0-CR7R8-, wherein R6, R7, and R8 are independently - H or methyl; (c) -CR6H-N(R9)-CR7R8-, wherein R6, R7, and R8 are independently -H or methyl; (d) -CH2-C(R9)(R10)-C(R7)(R8)-, wherein R7, R8, R9 and R10 are independently - H or -methyl, or both R7 and R8 are -F, R9 and R10 are independently -H or -methyl, or both R9 and R10 are -F, or R9 and R10 taken together are (0=), which together with the carbon to which they are attached forms a carbonyl group.