1353511-55-3

Basic information

• Product Name: 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyridine
• Synonyms: 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyridine
• CAS NO: 1353511-55-3
• Molecular Weight: 271.321
• Mol File: 1353511-55-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyridine(1353511-55-3)
• EPA Substance Registry System: 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyridine(1353511-55-3)

Safety Data

• Hazardous Substances Data: 1353511-55-3(Hazardous Substances Data)

Upstream product

• 1692-15-5 4-pyridylboronic acid 
• 4105-21-9 2-phenylimidazo[1,2-a]pyridine 
• 98-80-6 phenylboronic acid 
• 1373338-15-8 2-iodoimidazo[1,2-a]pyridine 
• 19524-06-2 4-bromopyridine hydrochloride 
• 74129-11-6 4-bromopyridine hydrobromide salt 
• 3999-05-1 2-chloroimidazo[1,2-a]pyridine 
• 4044-95-5 2-Phenyl-3-bromoimidazo<1,2-a>pyridine 
• 181219-01-2 4-pyridineboronic acid pinacol ester 
• 1021019-74-8 imidazo[1,2-a]pyridin-2-yl trifluoromethanesulfonate 
• 126202-06-0 2-(2-imino-1,2-dihydropyridin-1-yl)acetic acid 
• 112581-95-0 2-Bromoimidazo[1,2-a]pyridine 
• 504-29-0 2-aminopyridine 
• 1120-87-2 4-bromopyridin 

Relevant articles and documents

Regiocontrolled functionalization of 2,3-dihalogenoimidazo[1,2-a]pyridines by Suzuki-Miyaura and Sonogashira cross-coupling reactions

An efficient method for regiocontrolled functionalization of 2,3-dihalogenoimidazo[1,2-a]pyridine was developed. This sequence allowed the selective introduction of aryl, heteroaryl, alkyl and alkynyl substituents at both 2- and 3-positions, by using Suzu

Efficient access to 2,3-diarylimidazo[1,2-a ]pyridines via a one-pot, ligand-free, palladium-catalyzed three-component reaction under microwave irradiation

An expeditious one-pot, ligand-free, Pd(OAc)2-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of 2,3-diarylimidazo[1,2-a]pyridines analogues.

Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents

A novel series of 2,3-diarylimidazo[1,2-a]pyridines was synthesized and evaluated for their antileishmanial activities. Four derivatives exhibited good activity against the promastigote and intracellular amastigote stages of Leishmania major, coupled with a low cytotoxicity against the HeLa human cell line. The impact of compound lipophilicity on antiparasitic activities was investigated by Log D comparison. Although LmCK1 could be the parasitic target for three compounds (13, 18, 21), the inhibition of another target is under study to explain the antileishmanial effect of the most promising compounds.