4044-95-5

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2-phenyl-imidazo[1,2-a]pyridine is used as a potential active pharmaceutical ingredient for the development of new drugs. Its unique structure and properties make it a candidate for further research and development in the field of medicinal chemistry. 3-BROMO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE's potential pharmacological activities, such as anticancer, antimicrobial, and antiviral properties, make it a promising candidate for the treatment of various diseases and conditions.
Used in Medicinal Chemistry Research:
3-Bromo-2-phenyl-imidazo[1,2-a]pyridine is used as a research compound in medicinal chemistry. Its structure and properties can be further explored and modified to develop new drugs with improved efficacy and safety profiles. 3-BROMO-2-PHENYL-IMIDAZO[1,2-A]PYRIDINE's potential applications in various therapeutic areas, such as oncology, infectious diseases, and virology, make it an interesting target for drug discovery and development efforts.
Used in Drug Synthesis:
3-Bromo-2-phenyl-imidazo[1,2-a]pyridine can be used as a key intermediate in the synthesis of other related compounds with potential pharmaceutical applications. Its unique structure and functional groups can be utilized in various chemical reactions to generate new derivatives with improved pharmacological properties. This makes it a valuable building block in the development of novel drug candidates.

InChI:InChI=1/C13H9BrN2/c14-13-12(10-6-2-1-3-7-10)15-11-8-4-5-9-16(11)13/h1-9H

Upstream product

• 3672-37-5 3-nitroso-2-phenylimidazo<1,2-a>pyridine 
• 4105-21-9 2-phenylimidazo[1,2-a]pyridine 
• 1883-96-1 N-benzylidenepyridin-2-amine 
• 75-25-2 Bromoform 
• 504-29-0 2-aminopyridine 
• 112581-95-0 2-Bromoimidazo[1,2-a]pyridine 
• 126202-06-0 2-(2-imino-1,2-dihydropyridin-1-yl)acetic acid 
• 1021019-74-8 imidazo[1,2-a]pyridin-2-yl trifluoromethanesulfonate 
• 3999-05-1 2-chloroimidazo[1,2-a]pyridine 
• 98-80-6 phenylboronic acid 
• 110-86-1 pyridine 
• 57957-24-1 N-(1-phenylvinyl)acetamide 
• 1373338-15-8 2-iodoimidazo[1,2-a]pyridine 
• 98-86-2 acetophenone 

Downstream Products

• 1353511-55-3 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyridine 
• 85102-26-7 2,3-diphenyl-1H-imidazo[1,2-a]pyridine 
• 869583-82-4 2-phenyl-3-(2-phenylethynyl)imidazo[1,2-a]pyridine 
• 34658-68-9 3-methyl-2-phenyl-1H-imidazo[1,2-a]pyridine 
• 1416319-49-7 2-phenyl-3-(p-tolyl)imidazo[1,2-a]pyridine 
• 1416319-50-0 3-(4-methoxyphenyl)-2-phenylimidazo[1,2-a]pyridine 
• 1116088-85-7 methyl (E)-3-(2-phenylimidazo[1,2-a]pyridin-3-yl)acrylate 
• 4105-21-9 2-phenylimidazo[1,2-a]pyridine 
• 22244-94-6 3-nitro-2-(4'-nitrophenyl)imidazo[1,2-a]pyridine 
• 22244-95-7 3-bromo-2-(4'-nitrophenyl)imidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

Oxidative C-H/C-H Annulation of Imidazopyridines and Indazoles through Rhodium-Catalyzed Vinylene Transfer

Transition-metal-catalyzed C-H activation followed by oxidative annulation with alkynes has been an efficient synthetic tool for the assembly of various polyaromatic scaffolds. Despite the substantial progress in this field, it is still a significant chal

Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors

Despite the therapeutic relevance of δ-containing γ-aminobutyric acid type A receptors (GABAARs) and the need for δ-selective compounds, the structural determinants for the mode and molecular site of action of δ-selective positive allosteric modulator imi

Metal-free oxidative decarbonylative halogenation of fused imidazoles

An efficient strategy has been developed for the deformylative halogenation of carbaldehyde imidazo-fused heterocycles in the presence of TBHP controlled by temperature. A convenient and sequential functionalization (C8 to C3) portrays the synthetic utility of the current method.N-Heterocycle benzamide products were also observedviathe ring opening of imidazopyridines through the cleavage of C-C bond at high temperatures. Features of this method include temperature-controlled excellent regioselectivity, mild conditions and functional group tolerance.

Preparation method of C-3 haloimidazolium [1,2-a] pyridine derivative

The present invention discloses a method for preparing a C-3 haloimidazolium [1,2-a] pyridine derivative, belonging to the field of organic synthesis. The method took imidazolium [1,2-a] pyridine as the starting material, halide cuprous as the halogen sou

Difluorinative-hydroxylation and C-3 functionalization (halogenation/SCN/NO) of imidazopyridine using Selectfluor as fluorine source or oxidant respectively

An efficient route for the difluorinative-hydroxylation through dearomative difunctionalization of imidazopyridine using Selectfluor as fluorine source has been developed in an aqueous medium. The reaction proceeds through ionic followed by radical pathwa

Metal-free regioselective bromination of imidazo-heteroarenes: The dual role of an organic bromide salt in electrocatalysis

This paper represents an electrochemical transformation by demonstrating the dual role of an organic bromide salt, i.e., tetra-n-butylammonium bromide (TBAB), as a brominating agent and as an electrolyte for the regioselective bromination of several imida

Ultrasound-Promoted and Base-Mediated Regioselective Bromination of Imidazo[1,2- a ]pyridines with Pyridinium Tribromide

By using pyridinium tribromide as the bromo source, an efficient- and practical protocol for the synthesis of C3-brominated imidazo-[1,2- a ]pyridines through ultrasound-promoted and Na 2CO 3-mediated regioselective bromination of im

A simple and efficient route to 2-arylimidazo[1,2-a]pyridines and zolimidine using automated grindstone chemistry

A green and efficient mechanochemical method for the synthesis of a series of 2-arylimidazo[1,2-a]pyridines was developed using an electrical grinder. I2 catalyzed mechanochemical grinding facilitates the cyclocondensation reaction between various aryl methyl ketones and 2-aminopyridines to afford 2-arylimidazo[1,2-a]pyridines in good yields at ambient temperature. The method was successfully used for the gram-scale synthesis of a marketed drug, zolimidine. The noticeable advantages of this environmentally sustainable protocol include mild conditions, simple instrumentation, inexpensive catalyst, atom economy, short reaction time etc.

Electrochemical oxidative iodination of imidazo[1,2-a]pyridines using NaI as iodine source

An electrochemical oxidative iodination of imidazo[1,2-a]pyridines is achieved in this study. This reaction utilizes NaI as an iodine source and a supporting electrolyte under metal-free and exogenous chemical oxidant-free reaction conditions. The present

C3-site halogenation method of 2-phenylimidazo [1, 2-alpha] pyridine compound

The invention belongs to the technical field of organic synthesis, and specifically relates to a C3 site halogenation method of a 2-phenylimidazo [1, 2-alpha] pyridine compound, and the method comprises the following steps: in an air environment, by using