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1355049-95-4

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1355049-95-4 Usage

General Description

The chemical "(2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile" is a complex organic compound with a molecular structure containing a tetrahydrofuran ring, a carbonitrile group, and a tricyclic pyrrolo[2,1-f][1,2,4]triazine moiety. It has a chiral configuration with two stereocenters at the second and third carbon positions. The compound has a dihydroxy and hydroxymethyl substituents attached to the tetrahydrofuran ring. It contains an aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group and a carbonitrile functional group, making it potentially useful in organic synthesis, medicinal chemistry, or as a building block for more complex molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 1355049-95-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,5,0,4 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1355049-95:
(9*1)+(8*3)+(7*5)+(6*5)+(5*0)+(4*4)+(3*9)+(2*9)+(1*5)=164
164 % 10 = 4
So 1355049-95-4 is a valid CAS Registry Number.

1355049-95-4Relevant articles and documents

Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents

Bouton, Jakob,Maes, Louis,Karalic, Izet,Caljon, Guy,Van Calenbergh, Serge

, (2021)

The kinetoplastid parasites Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are the causative agents of neglected tropical diseases with a serious burden in several parts of the world. These parasites are incapable of synthesizing purines de nov

METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS

-

, (2016/05/19)

Provided are compounds, methods, and pharmaceutical compositions for treating Filoviridae vims infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula (IV): The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.

Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides

Cho, Aesop,Saunders, Oliver L.,Butler, Thomas,Zhang, Lijun,Xu, Jie,Vela, Jennifer E.,Feng, Joy Y.,Ray, Adrian S.,Kim, Choung U.

scheme or table, p. 2705 - 2707 (2012/05/20)

A series of 1′-substituted analogs of 4-aza-7,9-dideazaadenosine C-nucleoside were prepared and evaluated for the potential as antiviral agents. These compounds showed a broad range of inhibitory activity against various RNA viruses. In particular, the whole cell potency against HCV when R = CN was attributed to inhibition of HCV NS5B polymerase and intracellular concentration of the corresponding nucleoside triphosphate.

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