1355050-11-1

Basic information

• Product Name: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
• Synonyms: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
• CAS NO: 1355050-11-1
• Molecular Weight: 602.584
• Mol File: 1355050-11-1.mol
• Article Data: 8

Chemical Properties

• Density: 1.47±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(1355050-11-1)
• EPA Substance Registry System: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(1355050-11-1)

Safety Data

• Hazardous Substances Data: 1355050-11-1(Hazardous Substances Data)

Usage

Uses

Remdesivir (Diastereomeric Mixture) is an impurity of Remdesivir(CAS#:1809249-37-3); small molecule GS-?5734 with therapeutic efficacy against Ebola virus in rhesus monkeys.

Upstream product

• 1355049-92-1 2-ethylbutyl (2S)-2-{[chloro(phenoxy)phosphoryl]amino}propanoate 
• 1191237-69-0 (2R,3R,4S,5R)?2?(4?aminopyrrolo[1,2?f][1,2,4]triazin?7?yl)?3,4?dihydroxy?5?(hydroxymethyl)tetrahydrofuran?2?carbonitrile 
• 946511-97-3 2-ethylbutyl (S)-2-aminopropanoate hydrochloride 
• 1355049-95-4 (2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 
• 261909-49-3 phenyl(isopropoxy-L-alaninyl) phosphorochloridate 
• 770-12-7 O-phenyl phosphorodichloridate 
• 1439900-56-7 (2S)-2-ethylbutyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate 
• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 
• 14233-64-8 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-dihydro-furan-2-one 
• 159326-68-8 pyrrolo[2,1-f][1,2,4]triazin-4-amine 
• 1355357-49-1 (2R,3R,4R,5R)‐2‐{4‐aminopyrrolo[2,1‐f][1,2,4]triazin‐7‐yl}‐3,4‐bis(benzyloxy)‐5‐[(benzyloxy)methyl]tetrahydrofuran‐2‐carbonitrile 
• 1770840-43-1 7-iodopyrrolo-[2,1-f][1,2,4]-triazin-4-amine 
• 1911578-98-7 (2S)-2-(((perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoic acid 2-ethylbutyl ester 
• 1191237-68-9 (3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy) methyl)tetrahydrofuran-2-carbonitrile 

Downstream Products

• 1911578-75-0 (2S)-2-ethylbutyl 2-(((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
• 1809249-37-3 (2S)-2-ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

Relevant articles and documents

Preparation and analysis method of Sedellovir isomer

Through the preparation method provided by the invention, high-purity isomer compounds can be obtained; and the analysis method provided by the invention can realize effective separation of isomers and Sedgetalis, and has the advantages of simple and conv

Application of nucleoside compound, medicine and preparation method thereof

The invention relates to application of a nucleoside compound to preparation of a medicine for treating feline stomatitis, a medicine and a preparation method thereof. The nucleoside compound has a structure as shown in a formula (1): (please see the spec

METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS

Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.