135508-70-2Relevant academic research and scientific papers
Cephalosporin nitrogen mustard carbamate prodrugs for 'ADEPT'
Alexander,Beeley,O'Driscoll,O'Neill,Millican,Pratt,Willenbrock
, p. 3269 - 3272 (1991)
A series of cephalosporin carbamates, functionalised with masked nitrogen mustards has been synthesised. There are potential prodrugs for interaction with a monoclonal antibody-β-lactamase tumor targeting system. The β-lactamase catalysed hydrolysis to ge
