13552-93-7

Basic information

• Product Name: 2-phenylethanesulfonic acid
• CAS NO: 13552-93-7
• Molecular Formula: C₈H₉O₃S*Na
• Molecular Weight: 186.2282
• Mol File: 13552-93-7.mol
• Article Data: 2

Chemical Properties

• Density: 1.322g/cm³
• Refractive Index: 1.572
• CAS DataBase Reference: 2-phenylethanesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylethanesulfonic acid(13552-93-7)
• EPA Substance Registry System: 2-phenylethanesulfonic acid(13552-93-7)

Safety Data

• Hazardous Substances Data: 13552-93-7(Hazardous Substances Data)

Upstream product

• 60-12-8 2-phenylethanol 
• 100-42-5 styrene 
• 103-63-9 1-phenyl-2-bromoethane 

Downstream Products

• 1433543-50-0 N-hydroxy-2-(2-phenylethylsulfonamido)acetamide 
• 1156840-85-5 C₁₁H₁₅NO₄S 
• 4025-71-2 2-phenylethylsulfonyl chloride 

Relevant articles and documents

Discovery of a new class of potent MMP inhibitors by structure-based optimization of the arylsulfonamide scaffold

A new class of potent matrix metalloproteinase (MMP) inhibitors designed by structure-based optimization of the well-known arylsulfonamide scaffold is presented. Molecules show an ethylene linker connecting the sulfonamide group with the P1' aromatic portion and a D-proline residue bearing the zinc-binding group. The affinity improvement provided by these modifications led us to discover a nanomolar MMP inhibitor bearing a carboxylate moiety as zinc-binding group, which might be a promising lead molecule. Notably, a significant selectivity for MMP-8, MMP-12, and MMP-13 was observed with respect to MMP-1 and MMP-7.