135546-48-4Relevant academic research and scientific papers
CMP-Sialate Synthetase from Neisseria meningitidis - Overexpression and Application to the Synthesis of Oligosaccharides Containing Modified Sialic Acids
Knorst, Marion,Fessner, Wolf-Dieter
, p. 698 - 710 (2007/10/03)
The gene siaB encoding the CMP-sialate synthetase [EC 2.7.7.43] from Neisseria meningitidis serogroup B was subcloned for overexpression in Escherichia coli K12 using the expression vector pKK223-3. With the recombinant strain, 7500 U of synthetase could
Synthesis of CMP-sialic acid conjugates: Substrates for the enzymatic synthesis of natural and designed sialyl oligosaccharides
Chappell, Mark D.,Halcomb, Randall L.
, p. 11109 - 11120 (2007/10/03)
The syntheses of several congeners of CMP-NeuAc are described. These compounds are substrates for enzymatic glycosylation.
