145552-07-4Relevant academic research and scientific papers
Synthesis of potential inhibitors of hemagglutination by influenza virus: Chemoenzymic preparation of N-5 analogs of N-acetylneuraminic acid
Sparks, Michelle A.,Williams, Kevin W.,Lukacs, Christine,Schrell, Andreas,Priebe, Gregory,Spaltenstein, Andreas,Whitesides, George M.
, p. 1 - 12 (2007/10/02)
A chemoenzymic route to neuraminic acid 2 is described. This method is based on conversion of N-carbobenzoxymannosamine (ManCBz) 3 to N-carbobenzoxyneuraminic acid (Neu5CBz) 4, catalyzed by Neu5Ac aldolase. The Neu5CBz 4 was converted to the α-methyl glyc
