1355646-93-3 Usage
Description
1-(3-tert-butyl-5-(6-hydroxynaphthalen-2-yl)-4-methoxyphenyl)-pyrimidine-2,4(1H,3H)-dione is a complex chemical compound characterized by a pyrimidine backbone with a tert-butyl group, a 6-hydroxynaphthalen-2-yl group, and a 4-methoxyphenyl group as substituents. This synthetic molecule holds potential pharmaceutical applications and is likely under investigation as a prospective drug candidate. 1-(3-tert-butyl-5-(6-hydroxynaphthalen-2-yl)-4-methoxyphenyl)-pyrimidine-2,4(1H,3H)-dione's structure, featuring hydroxynaphthalen-2-yl and methoxyphenyl groups, suggests it may possess antioxidant and anti-inflammatory properties, making it a promising candidate for drug development and further research to ascertain its precise molecular and biological characteristics.
Uses
Used in Pharmaceutical Industry:
1-(3-tert-butyl-5-(6-hydroxynaphthalen-2-yl)-4-methoxyphenyl)-pyrimidine-2,4(1H,3H)-dione is used as a potential drug candidate for its possible antioxidant and anti-inflammatory properties, which could be beneficial in the development of treatments for various diseases and conditions.
Used in Research and Development:
In the field of chemical and biological research, this compound serves as a subject for further investigation to understand its molecular properties, potential interactions with biological systems, and its applicability in the creation of new therapeutic agents.
Please note that without specific details on the applications from the provided materials, the uses listed are general and based on the compound's structural features and potential properties. Further research and development would be necessary to confirm its utility in specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1355646-93-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,5,6,4 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1355646-93:
(9*1)+(8*3)+(7*5)+(6*5)+(5*6)+(4*4)+(3*6)+(2*9)+(1*3)=183
183 % 10 = 3
So 1355646-93-3 is a valid CAS Registry Number.
1355646-93-3Relevant articles and documents
Discovery and Development of Metal-Catalyzed Coupling Reactions in the Synthesis of Dasabuvir, an HCV-Polymerase Inhibitor
Barnes, David M.,Shekhar, Shashank,Dunn, Travis B.,Barkalow, Jufang H.,Chan, Vincent S.,Franczyk, Thaddeus S.,Haight, Anthony R.,Hengeveld, John E.,Kolaczkowski, Lawrence,Kotecki, Brian J.,Liang, Guangxin,Marek, James C.,McLaughlin, Maureen A.,Montavon, Donna K.,Napier, James J.
, p. 4873 - 4892 (2019/02/05)
Dasabuvir (1) is an HCV polymerase inhibitor which has been developed as a part of a three-component direct-acting antiviral combination therapy. During the course of the development of the synthetic route, two novel coupling reactions were developed. First, the copper-catalyzed coupling of uracil with aryl iodides, employing picolinamide 16 as the ligand, was discovered. Later, the palladium-catalyzed sulfonamidation of aryl nonaflate 33 was developed, promoted by electron-rich palladium complexes, including the novel phosphine ligand, VincePhos (50). This made possible a convergent, highly efficient synthesis of dasabuvir that significantly reduced the mutagenic impurity burden of the process.
