135663-75-1

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 37428-58-3 (E)-β-iodocrotyl alcohol 

Downstream Products

• 135663-76-2 (E)-(4S,6S,9R)-1-Benzenesulfonyl-6-benzyloxy-10-(tert-butyl-diphenyl-silanyloxy)-3,9-dimethyl-dec-2-en-4-ol 
• 135663-83-1 Acetic acid (E)-(5S,7S,10R)-2-benzenesulfonyl-7-benzyloxy-11-(tert-butyl-diphenyl-silanyloxy)-1-((E)-(3S,5R)-5-[1,3]dithian-2-yl-3-methyl-hex-1-enyl)-5-methoxy-4,10-dimethyl-undec-3-enyl ester 
• 135663-81-9 Acetic acid (E)-(5S,7S,10R)-2-benzenesulfonyl-7-benzyloxy-11-(tert-butyl-diphenyl-silanyloxy)-1-((E)-(3S,5R)-3,5-dimethyl-6-oxo-hex-1-enyl)-5-methoxy-4,10-dimethyl-undec-3-enyl ester 
• 135663-84-2 ((8E,10Z,12E)-(2R,5S,7S,14S,16R)-10-Benzenesulfonyl-5-benzyloxy-16-[1,3]dithian-2-yl-7-methoxy-2,8,14-trimethyl-heptadeca-8,10,12-trienyloxy)-tert-butyl-diphenyl-silane 
• 135663-85-3 (5E,7Z,9E)-(2R,4S,11S,13S,16R)-8-Benzenesulfonyl-13-benzyloxy-17-(tert-butyl-diphenyl-silanyloxy)-11-methoxy-2,4,10,16-tetramethyl-heptadeca-5,7,9-trienal 
• 135663-78-4 ((E)-(2R,5S,7S)-10-Benzenesulfonyl-5-benzyloxy-7-methoxy-2,8-dimethyl-dec-8-enyloxy)-tert-butyl-diphenyl-silane 
• 135663-77-3 (E)-(6S,9R)-1-Benzenesulfonyl-6-benzyloxy-10-(tert-butyl-diphenyl-silanyloxy)-3,9-dimethyl-dec-2-en-4-one 
• 150988-54-8 [(E)-(4S,6S,9R)-6-(tert-Butyl-dimethyl-silanyloxy)-4-methoxy-3,9-dimethyl-10-triethylsilanyloxy-dec-2-ene-1-sulfonyl]-benzene 
• 150988-47-9 (E)-(2R,5S)-10-Benzenesulfonyl-5-benzyloxy-2,8-dimethyl-7-oxo-dec-8-enoic acid ethyl ester 
• 150988-53-7 (E)-(2R,5S,7S)-10-Benzenesulfonyl-5-(tert-butyl-dimethyl-silanyloxy)-7-methoxy-2,8-dimethyl-dec-8-enoic acid methyl ester 
• 150988-48-0 (E)-(2R,5S)-10-Benzenesulfonyl-5-hydroxy-2,8-dimethyl-7-oxo-dec-8-enoic acid ethyl ester 
• 150988-52-6 (E)-(2R,5S,7S)-10-Benzenesulfonyl-5-hydroxy-7-methoxy-2,8-dimethyl-dec-8-enoic acid methyl ester 
• 150988-49-1 (E)-(2R,5S,7S)-10-Benzenesulfonyl-5,7-dihydroxy-2,8-dimethyl-dec-8-enoic acid ethyl ester 
• 150988-51-5 (3R,6S)-6-((E)-(S)-5-Benzenesulfonyl-2-methoxy-3-methyl-pent-3-enyl)-3-methyl-tetrahydro-pyran-2-one 

Relevant academic research and scientific papers

Application of the Ibuka-Yamamoto Reaction to a Problem in Stereochemical Communication: A Strategy for the Stereospecific Synthesis and Stabilization of the Triene Substructure of Rapamycin through Sulfone Substitution

The aldehydes 49 and 55 corresponding to carbons 13-30 in a projected total synthesis of rapamycin have been synthesized.The LACDAC technology was used to elaborate dithiane enal 5.The aldehyde 4 was synthesized from D-(+)-glucose.A critical element of th