1357024-86-2

Upstream product

• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 121-33-5 vanillin 
• 855242-15-8 1-(benzyloxy)-2,3,5-trimethoxybenzene 
• 57230-04-3 3,4-dimethoxy-5-benzyloxybenzaldehyde 
• 29865-90-5 3-hydroxy-4,5-dimethoxybenzaldehyde 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 3934-87-0 5-hydroxyvanillin 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 
• 54917-02-1 2-(benzyloxy)-4,6-dimethoxybenzaldehyde 
• 1835-11-6 4-benzyloxy-3-methoxyacetophenone 
• 52249-82-8 4-(benzyloxy)-2,3,6-trimethoxybenzaldehyde 
• 1357024-84-0 2-(benzyloxy)-4,6-dimethoxyphenol 
• 708-76-9 2-hydroxy-4,6-dimethoxybenzaldehyde 

Downstream Products

• 912957-28-9 Viscolin 

Relevant academic research and scientific papers

A concise synthesis of viscolin, and its anti-inflammatory effects through the suppression of iNOS, COX-2, ERK phosphorylation and proinflammatory cytokines expressions

In the present report, a concise synthesis of viscolin (1) has been achieved. The anti-inflammatory effect of viscolin was investigated in vitro and in vivo. Viscolin blocked the expression of iNOS and COX-2, and it also inhibited the ERK for the activation of NF-κB in LPS-stimulated RAW 264.7 macrophages. Western blotting and immunohistochemical analysis revealed that viscolin decreased Carr-induced iNOS and COX-2 expressions. These results could help to deduce the anti-inflammatory mechanisms.